Sentences with phrase «myoblasts in»

Although the metabolic responses observed are consistent with the cellular consequences of osteocalcin exposure in pancreatic β - cells and myoblasts in vitro (27 — 29, 61), the metabolic effects of exercise and WBV may not be dependent on osteocalcin per se.

His team have begun recolonising the primate scaffolds with human cells that line blood vessels, the first step towards human - scale biolimb development, and have started experiments using human myoblasts in rats instead of the mice ones.

Not exact matches

A decline in expression of REV - ERB leads to myoblast differentiation.

The study «Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation» is published in the journal Scientific Reports.

The fusion of myoblasts is a critical step in the formation of embryonic muscle fibers as it determines muscle size, among other things.

«We were able to identify the receptor BAI3, a protein at the surface of myoblasts, as one of the crucial missing links in the fusion of muscle cells,» adds Dr. Côté.

Next, he injected a mixture of cells from mice that included myoblasts, the cells that grow into muscle, in the cavities of the scaffold normally occupied by muscle.

Using myoblasts from DNM2 - mutated patients and using myoblasts and muscles from a knock - in mouse model of DNM2 - related myopathy, we analyzed structure of costameres by biochemical and immunocytochemical approaches, as well as their ultrastructure.

Modulation of Protein Quality Control and Proteasome to Autophagy Switch in Immortalized Myoblasts from Duchenne Muscular Dystrophy Patients.

Currently, back at the University of warsaw, she heads the Department of Cytology which investigates the potential of various stem cells to differentiate into myoblasts and to participate in the regeneration of skeletal muscle.

He presented results from both SMA mouse models and patients that demonstrated SMN depletion results in muscle - intrinsic defects such as reduced satellite cell number, a delay in the myogenic program, reduced myoblast fusion, and molecular homeostasis disruption.

In a subsequent study, they used CRISPR with two gRNAs to delete exon 51 or exons 45 - 55 in patient myoblasts; when injected into DMD mice, these cells expressed functional dystrophiIn a subsequent study, they used CRISPR with two gRNAs to delete exon 51 or exons 45 - 55 in patient myoblasts; when injected into DMD mice, these cells expressed functional dystrophiin patient myoblasts; when injected into DMD mice, these cells expressed functional dystrophin.

Addgene depositor Charles Gersbach used paired zinc finger nucleases to remove exon 51 in DMD patient myoblasts.