Sentences with word «myocyte»
A myocyte is a type of muscle cell. It is responsible for contracting and relaxing to enable movement in our bodies. Full definition
Differential Sarcomere and Electrophysiological Maturation of Human iPSC - Derived Cardiac Myocytes in Monolayer vs. Aggregation - Based Differentiation Protocols.
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Myofibrils, the functional units of myocytes, composed of actin and myosin filaments spanning the length of the muscle cell, do not serve as substrate for the proteasome in their native state (45).
Myocyte enhancer factor 2C, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)- enhanced mineralization.
By identifying the epigenetic determinants and the responsible epigenetic enzymes controlling these different forms of cardiac myocyte hypertrophy, as well as how the epigenetic modifiers are themselves regulated by micoRNAs, we provide a potential strategy for epigenetic therapy for adverse cardiac remodelling.
Miostatin (also known as growth differentiation factor 8 or GDF - 8), is a myokine produced and released by myocytes that inhibits myogenesis, i.e. growth and differentiation in muscle cells.
Nadiia Rozmaritsa (Ravens, TUD)-- «Regulation of Ca2 + - handling proteins by nitric oxide in atrial myocytes from patients in sinus rhythm and atrial fibrillation» (2012)
In another method, 3D heart muscle was reconstituted with cardiac myocytes derived from human induced pluripotent stem cells (iPSCs).
These tests indicate that myomerger - deficient muscle cells called myocytes differentiate and form the contractile unit of muscle (sarcomeres), but they do not join together to form fully functioning muscle tissue.
When someone suffers a heart attack, it triggers the process of the UPR inside myocytes (heart cells).
This coupling, termed O - GlcNAcylation, has favorable effects on disease - injured cells, including myocytes.
Hydrogen peroxide - mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart.
Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction.
Expression of MyoD, a skeletal muscle - specific transcriptional regulator, activated the expression of the Cdk inhibitor p21 during differentiation of murine myocytes and in nonmyogenic cells.
We do this by studying new cells types in the heart that can contribute to the generation of new myocytes and by defining the mechanisms that can trigger cardiomyocyte division upon damage.
We then combined confocal microscopy and electrophysiology to explore the interactions between temperature, adrenergic stimulation and contraction frequency on the temporal and spatial properties of Δ [Ca2 +] i, and the excitation profiles of AP and ICa in isolated myocytes.
Cardiac myocyte cross-sectional area and volume fraction of interstitial fibrosis were both significantly higher in untreated dogs with HF than in normal dogs.
Myocyte hypertrophy develops during the late phase (after 72 hours) as a compensatory response for the changes in heart muscle architecture.
Association between connexin 40 and potassium voltage-gated channel subfamily A member 5 expression in the atrial myocytes of patients with atrial fibrillation.
Mesenchymal stem cells (MSC) have been identified in the bone marrow (BM) as multipotent non-hematopoietic progenitor cells that differentiate into osteoblasts, adipocytes, chondrocytes, tenocytes, skeletal myocytes, and cells of visceral mesoderm1 - 3.
«We were able to see for the first time, in 3D, where calcium waves come from in cardiac myocytes,» he explains.
Besides osteoblasts, mesenchymal stem cells can also differentiate into the chondrocyte cells that make cartilage, the myocyte cells that help form muscles and the adipocytes, or fat cells.
The study also found that the zebrafish ECM protected human cardiac myocytes — specialized cells that form heart muscle — from stresses.
As a scholar and scientist, Dr. Williams discovered genes, proteins and pathways that control development, proliferation, cell size and differentiation of cardiac and skeletal muscle cells (myocytes).
Perivascular cells, including pericytes in the smallest blood vessels (e.g., microvessels) and ARCs around larger ones, express mesenchymal stem cell markers and bear a multi-differentiation fate potential (differentiate into osteoblasts, chondrocytes, adipocytes, smooth muscle cells and myocytes) similar to that documented for MSCs in vitro.
All components of the myocardium (myocytes, extracellular matrix, and capillary microcirculation) undergo complex, dynamic, and time - dependent changes resulting in significant necrosis of heart muscle tissue.
His research interests in the laboratory include thyroid hormone action in the heart, as well as studies related to diabetic cardiomyopathy and the effects of excessive enzymatic protein glycosylation in cardiac myocytes and their influence on heart function.
Similar to B -LRB--) / B -LRB--) mice, most B (a *) / B (a *) mice died late in embryonic development with structural cardiac defects and impaired cytokinesis of the cardiac myocytes.
Embryonic cardiac fibroblasts promote myocyte proliferation, while adult fibroblasts promote myocyte hypertrophy,» said Masaki Ieda, MD, PhD, Gladstone postdoctoral fellow and lead author on the study.
Thus, although NMHC II - A can substitute for NMHC II - B to maintain integrity of the spinal canal, NMHC II - B plays an isoform - specific role during cytokinesis in cardiac myocytes and in migration of the facial and pontine neurons.
Image shows strong immunopositivity at the membranes of cardiomyocytes (invaginations of immunostaining show points of branching of each myocyte).
«It can stimulate the expression of PGC - 1α and mitochondrial biogenesis in the cardiac myocytes, and this process might provide a potential adaptive mechanism for cardiac myocytes to increase ATP output and minimize hypoxic damage to the heart [xvi].»
Skeletal muscles consist of muscle cells, also known as muscle fibers or myocytes.
Bone marrow contains the base cells that create osteoblasts, chondrocytes (cartilage cells), myocytes (muscle cells), and adipocytes (fat cells).
Reactive oxygen species play an essential role in IGF - I signaling and IGF - I - induced myocyte hypertrophy in C2C12 myocytes.
«Diazepam Increases Intracellular Calcium and Contraction Following Beta Adrenergic Stimulation In Myocytes»; Anesthesia & Analgesia 90: S56, 2000.