Greater stimulation
of myofibrillar protein synthesis with ingestion of whey protein isolate vs. micellar casein at rest and after resistance exercise in elderly men.
Whey protein has demonstrated the ability to
enhance myofibrillar protein synthesis, in doses of 20g in young adults and 40g in aging muscle by research scientist at the Department of Kinesiology at McMaster University in Canada.
Conclusion «The protein intake references derived herein could be considered when setting protein intakes for older men (based on a balanced three - meal daily protein intake) and when developing nutritional strategies to
maximize myofibrillar protein synthesis and, potentially, maintain muscle mass», the researchers write.
The first novel finding of this study was that mTOR signaling and rates
of myofibrillar protein synthesis (MPS) following concurrent resistance, continuous and intermittent high - intensity exercise, designed to mimic the metabolic profile of many team sports, were impaired during the early (8 h) recovery phase by the ingestion of large amounts (1.5 g • kg − 1 BM) of alcohol.
«Our results have implications for nutrient formulations designed to support increased muscle protein anabolism in the elderly and suggest that whey protein offers clear advantages to soy protein in its capacity to support both rested and postexercise increases
in myofibrillar protein synthesis», the researchers wrote.
The biopsies have shown increased
myofibrillar protein synthesis in the time interval between the first and sixth hour.
While the initiation of
myofibrillar protein synthesis is influenced by a number of factors, mTOR is a key regulatory factor that results in a direct increase in myofibrillar protein synthesis.
Ingestion of 40 g protein before sleep increases
myofibrillar protein synthesis rates during overnight sleep.