Jesty SA, Steffey MA, Lee FK, et al. ckit + precursors support postinfarction
myogenesis in the neonatal, but not adult, heart.
In chick embryos, skeletal muscle formation is initiated by migrating Delta1 - expressing neural crest cells that trigger NOTCH signaling and
myogenesis in selected epithelial somite progenitor cells, which rapidly translocate into the nascent muscle to differentiate.
However, Setd7 expression increased with the progression of
myogenesis in vitro indicating the potential importance of this event for skeletal muscle development and regeneration in vivo.
We have recently shown that in avian embryos, muscle formation is initiated by Delta1 - positive neural crest cells migrating from the dorsal neural tube that, in passing, trigger NOTCH signalling and
myogenesis in selected epithelial somite progenitor cells, allowing them to migrate into the nascent muscle to differentiate.
Not exact matches
To assess the role of hlh - 1
in C. elegans
myogenesis, genetic deficiencies spanning the hlh - 1 locus were isolated after gamma irradiation.
Syndecan - 3 and Notch cooperate
in regulating adult
myogenesis.
Preliminary data we have now obtained further indicate that
in somite cells, the activation of the NOTCH pathway triggers a «signalling module» that couples the initiation of
myogenesis with the epithelial - mesenchymal transition (EMT) that allows them to migrate into the growing muscle.
In the course of this process, signals from the microenvironment instruct cycling MuSCs and control
myogenesis.
Pax - 7 up - regulation inhibits
myogenesis and cell cycle progression
in satellite cells: a potential mechanism for self - renewal.
Accordingly, our data suggests that the failure of regenerative
myogenesis to keep pace with disease progression
in DMD is not due to muscle stem cell exhaustion, but rather is due to a cell - autonomous deficiency
in asymmetric division.
In this study, Chazaud et al., evidenced that endothelial cells (ECs) and myogenic progenitor cells (MPCs) interacted to couple
myogenesis and angiogenesis during skeletal muscle regeneration.
Title: Muscle satellite cells are primed for
myogenesis, but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA - 31
in mRNP granules Authors: Crist CG, Montarras D, Buckingham M Date: 2012 Publication Details: Cell Stem Cell 2012 Jul 6:11 (1): 118 - 126
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