Sentences with word «myogenic»

Characterized other proteins and pathways that modulate proliferation and differentiation of myogenic stem cells, hypertrophic growth of the heart, mitochondrial biogenesis and fiber type — specific gene expression in skeletal muscles.

«Starting with pluripotent stem cells that are not muscle cells, but can become all existing cells in our body, allows us to grow an unlimited number of myogenic progenitor cells,» said Nenad Bursac, professor of biomedical engineering at Duke University.

Discovered a novel transcription factor that modulates important steps in the transitions of adult myogenic stem cells to and from quiescence during muscle regeneration.

Deletion of Setd7 in MuSCs revealed a block in myogenic differentiation and while the loss of Setd7 function in vivo did permit muscle development in mice, the lack of this methyltransferase impaired regenerative responses following acute injury.

Survival motor neuron protein deficiency impairs myotube formation by altering myogenic gene expression and focal adhesion dynamics.

Willoughby DS and Rosene J.M. Effects of oral creatine and resistance training on myogenic regulatory factor expression.

Myogenic response of human skeletal muscle to 12 weeks of resistance training at light loading intensity

Effect of Electrode Montage and Head Position on Air - Conducted Ocular Vestibular Evoked Myogenic Potential.

The effects of ergogenic compounds on myogenic satellite cells.

Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

«When your body is forced to adapt to the increased demands of a heavier weight, it responds by building more contractile proteins within the muscle, which increases muscle density and muscle tone (myogenic tone).»

Efficacy of 3 days / wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults.

However, the authors found no evidence for a role of Setd7 in histone methylation or as a partner of MyoD in MuSCs and instead, they discovered that Setd7 interacted with - catenin and modulated its methylation status to promote nuclear translocation and the transcription of Wnt - responsive myogenic genes.

The aim or our team is to understand the role of the interactions myogenic cells develop with their environment in the regulation of skeletal muscle regeneration and their impact in the pathological context of degenerating myopathies.

Sciorati C, Monno A, Ascherman DP, Seletti E, Manfredi AA, Rovere - Querini P. Required role of apoptotic myogenic precursors and toll - like receptor stimulation for the establishment of autoimmune myositis in experimental murine models.

Darabi R, Arpke RW, Irion S, et al., Human ES - and iPS - derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice.

However, researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and differentiation of induced myogenic progenitor cells (iMPCs) from hPSCs into the first entirely hPSC - derived 3D muscle tissues that survive, vascularize, and maintain function following transplantation [5].

The self - renewing properties of satellite cells not only maintains the muscle stem cell population in the body, but also provides myogenic cells, which proliferate, differentiate, fuse, and lead to the formation of new myofibers whenever necessary to repair the damage.

This means that more ingredient is delivered to the site where it can be utilized effectively, ready to be delivered to the bloodstream and flood your muscles with potent myogenic factors needed to transcend into becoming a demigod!

Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma.

Judson RN, Quarta M, Oudhoff MJ, et al., Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential.

«We have discovered a pathway by which the Pax7 and myogenic potential of satellite cells is regulated.

According to Cardio Haters» Grant Lofthouse, who favours five sets of six reps, «When your body is forced to adapt to the increased demands of a heavier weight, it responds by building more contractile proteins within the muscle, which increases muscle density and muscle tone (myogenic tone).»

Efficacy of 3 days / wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults

Interestingly, treatment with a selective and potent small - molecule inhibitor of Setd7 activity (PFI - 2)[4] impaired - catenin translocation and myogenic gene expression, and thereby promoted the maintenance of MuSCs in an immature state.

Abstract We discovered that a subset of satellite cells in skeletal muscle are self - renewing stem cells that give rise to myogenic progenitors through asymmetric apical - basal cell divisions.

When committed to myogenic differentiation, SCs proliferate further, fuse to existing SkM fibers, and contribute new nuclei to the growing and regenerating fibers.

Review of «Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential» from Cell Stem Cell by Stuart P. Atkinson

We explore the roles of immune cells (inflammation), endothelial and peri-endothelial cells (angiogenesis) and interstitial cells (fibrosis) in both myogenic cell fate in normal healthy regenerating muscle and in the pathogenesis of muscular dystrophies.

Their work focusses on the genes that regulate the entry of cells into the myogenic programme.

Furthermore, the reversible nature of microRNA dependent silencing mechanisms may underlie the rapid activation of satellite cells that are poised to enter the myogenic program.

Using mouse skeletal muscle stem cells as a model, we show that accumulating transcripts specifying the myogenic program are not translated in quiescent satellite cells, but are repressed by the action of microRNAs and RNA binding proteins.

Skeletal muscle stem cells unable to phosphorylate eIF2 exit quiescence, activate the myogenic program and differentiate, but do not self - renew.

In this study, Chazaud et al., evidenced that endothelial cells (ECs) and myogenic progenitor cells (MPCs) interacted to couple myogenesis and angiogenesis during skeletal muscle regeneration.

Environment plays important roles in the behavior of muscle stem cells and myogenic cells, although the mechanisms are poorly unknown.

Ioannis Sgouralis (Mathematics, Duke, 2014) developed a computational model of renal autoregulation that dynamically represents the myogenic response and tubuloglomerular feedback at the whole kidney level.

There are myogenic stem cells or «satellite cells» surrounding the muscle cells.

Louis, M. et al., (2004) Creatine increases IGF - 1 and myogenic regulatory factor mRNA in C2C12 cells.

Since 1972 he turned to be a disciple and follower in the scientific plan from Dr. Quintiliano H. de Mesquita, who has developed the myogenic theory of myocardial infarction, accompanying him as a special collaborator until his death in 2000.