Sentences with phrase «myogenic cell»

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination.

In vitro experiments in myogenic cells initially suggested that IL - 15 was an anabolic factor for skeletal muscle, able to stimulate the accumulation of contractile protein in differentiated myotubes (8 — 10).

Neural cell adhesion molecule (NCAM) marks adult myogenic cells committed to differentiation.

Not exact matches

«Starting with pluripotent stem cells that are not muscle cells, but can become all existing cells in our body, allows us to grow an unlimited number of myogenic progenitor cells,» said Nenad Bursac, professor of biomedical engineering at Duke University.

Characterized other proteins and pathways that modulate proliferation and differentiation of myogenic stem cells, hypertrophic growth of the heart, mitochondrial biogenesis and fiber type — specific gene expression in skeletal muscles.

Furthermore, the reversible nature of microRNA dependent silencing mechanisms may underlie the rapid activation of satellite cells that are poised to enter the myogenic program.

Their work focusses on the genes that regulate the entry of cells into the myogenic programme.

Abstract We discovered that a subset of satellite cells in skeletal muscle are self - renewing stem cells that give rise to myogenic progenitors through asymmetric apical - basal cell divisions.

Using mouse skeletal muscle stem cells as a model, we show that accumulating transcripts specifying the myogenic program are not translated in quiescent satellite cells, but are repressed by the action of microRNAs and RNA binding proteins.

In this study, Chazaud et al., evidenced that endothelial cells (ECs) and myogenic progenitor cells (MPCs) interacted to couple myogenesis and angiogenesis during skeletal muscle regeneration.

Judson RN, Quarta M, Oudhoff MJ, et al., Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential.

Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

Review of «Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential» from Cell Stem Cell by Stuart P. Atkinson

He presented results from both SMA mouse models and patients that demonstrated SMN depletion results in muscle - intrinsic defects such as reduced satellite cell number, a delay in the myogenic program, reduced myoblast fusion, and molecular homeostasis disruption.

However, researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and differentiation of induced myogenic progenitor cells (iMPCs) from hPSCs into the first entirely hPSC - derived 3D muscle tissues that survive, vascularize, and maintain function following transplantation [5].

Louis, M. et al., (2004) Creatine increases IGF - 1 and myogenic regulatory factor mRNA in C2C12 cells.

The effects of ergogenic compounds on myogenic satellite cells.