Characterized other proteins and pathways that modulate proliferation and
differentiation of
myogenic stem cells, hypertrophic growth of the heart, mitochondrial biogenesis and fiber type — specific gene expression in skeletal muscles.
However, researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and
differentiation of induced
myogenic progenitor cells (iMPCs) from hPSCs into the first entirely hPSC - derived 3D muscle tissues that survive, vascularize, and maintain function following transplantation [5].