Sentences with phrase «myogenic satellite»

The effects of ergogenic compounds on myogenic satellite cells.

Not exact matches

Furthermore, the reversible nature of microRNA dependent silencing mechanisms may underlie the rapid activation of satellite cells that are poised to enter the myogenic program.

Abstract We discovered that a subset of satellite cells in skeletal muscle are self - renewing stem cells that give rise to myogenic progenitors through asymmetric apical - basal cell divisions.

Using mouse skeletal muscle stem cells as a model, we show that accumulating transcripts specifying the myogenic program are not translated in quiescent satellite cells, but are repressed by the action of microRNAs and RNA binding proteins.

He presented results from both SMA mouse models and patients that demonstrated SMN depletion results in muscle - intrinsic defects such as reduced satellite cell number, a delay in the myogenic program, reduced myoblast fusion, and molecular homeostasis disruption.