Sentences with phrase «myostatin function»

Loss of myostatin function is associated with an increase in muscle mass in mice, cows, and humans.

The muscle - building and fat - burning effects of human growth hormone are thought to be caused by GH's interference with myostatin function [21], and the muscle destroying effects of cortisol appear to be associated with higher concentrations of myostatin [22].

If myostatin does act systemically, the implication would be that local control of muscle growth can be influenced at least in part by myostatin being produced elsewhere in the body and that myostatin functions precisely as a chalone, as originally hypothesized by Bullough [25], [26] for the control for tissue growth in general.

Not exact matches

To determine whether the FLRG transgene was causing increased muscle growth by blocking myostatin activity, I examined the effect of combining the FLRG transgene with a loss - of - function mutation in the myostatin gene.

The function of myostatin appears to have been conserved across species, as inactivating mutations in the myostatin gene have been demonstrated to cause increased muscling in cattle [8]--[11], sheep [12], dogs [13] and humans [14].

There have been human trials of myostatin blockade via antibodies, for example, and there are even a few well - muscled natural human myostatin loss of function mutants.

From a biological point of view, the primary function of myostatin is the control of metabolism in order to support the immune system.

«Decreasing myostatin and inhibiting its function by GASP - 1 may play an important role in increasing muscle strength and mass by resistance training», they write.