Sentences with phrase «myostatin propeptide»

Gene therapy offers a shortcut to bulking up: At the University of Pennsylvania, H. Lee Sweeney is developing a way to turn the liver into a factory that churns out a muscle growth promoter called myostatin propeptide.

Not exact matches

Following proteolytic processing, the propeptide remains bound to the C - terminal dimer and maintains it in an inactive, latent complex [6], [19], [20], which represents one of the major forms of myostatin that circulates in the blood [21], [22].

Myostatin is synthesized as a precursor protein that undergoes proteolytic processing to generate an N - terminal propeptide and a C - terminal dimer, which is the biologically active species.

In addition to the propeptide, other binding proteins are capable of regulating myostatin activity in vitro, including follistatin [19], [21], FLRG [22], and Gasp - 1 [23].