Sentences with phrase «n't culture cells»

Not exact matches

(So far, the company's cell cultures are reported to be small, about the size of a postage stamp, and not fully functional.)

Cultured meat producers still have to source the first set of cells from an animal — even if it's just a small biopsy that doesn't require slaughter.

If I have a bunch of cells from a throat culture or other medical swab, that isn't a human life.

A cell in my brain is different from a cell not in my brain but, say, in a culture of cells in a dish.

While some still object to cells being taken from animals and used by scientists to grow clean meat in laboratories — and some just don't like the idea of eating a «cultured» steak created by men and women in white coats — others see the lab - grown meat revolution as key to solving the environmental crisis linked to meat eating.

Culturing stem cells by day, and audiences in dingy stand - up clubs by night, it wasn't until Helen Pilcher left the lab that she started basing her comedy on science.

Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.

With our human gut - on - a-chip, we can not only culture the normal gut microbiome for extended times, but we can also analyze contributions of pathogens, immune cells, and vascular and lymphatic endothelium, as well as model specific diseases to understand complex pathophysiological responses of the intestinal tract.»

In addition, mammalian cell cultures are not always an ideal medium: at times, it is simply too hard to produce proteins in this manner.

The team found several hundred that might do so and restore the protein to its functional shape; more than 30 did the job when tested in cell culture, although they don't know whether they attached to p53 in the pocket.

Yeast cultures normally do not exceed 100 million to 200 million cells per millilitre.

Milk glands, moreover, do not need the constant coddling required for cell cultures.

One of the 12 audience members was Ben Chao, a chemical engineer with a Ph.D. — not at all qualified to make a judgment on Scott's abilities in the area of «Approaches to Developing Serum - Free Media Formulations for Mammalian Cells in Culture.»

Most importantly, it wasn't toxic» to cell cultures, Lee explained.

When cells that produced IL - 21 were put in culture with synovial fibroblasts (which are the main contributors to joint inflammation in rheumatoid arthritis), they induced the production of proinflammatory cytokines by these synovial fibroblasts, and cells that do not produce IL - 21, did not demonstrate this same outcome.

In rats and tissue cultures of human nerve cells, these «beta sheet breakers» not only prevent amyloid plaques from forming, but also dissolve existing plaques.

«It is possible the researchers simply have not worked out adequate methods to maintain these cells long - term in culture,» he says.

However, this coupling does not exist in cell culture models with exogenously expressed c - MYC — the type of systems that are mainly used to investigate glutamine addiction in cancer.

It isn't clear exactly why the differences fade, Hochedlinger says, but it may be that the expression of embryonic genes is strengthened as the cells grow in culture, gradually overwriting the cells» old gene - expression patterns.

It seems we can now isolate the cells and study them in a pure culture, which is something that wasn't possible before.»

Through these effects, the PERY peptide reduced the proliferation of several (but not all) cancer cell lines in culture and inhibited the growth of a human breast cancer xenograft in mice.

The cell cultures still did not prove whether optogenetics would apply to brain cells inside living, freely moving mammals, however.

«Most adult stem cells can not be cultured in vitro without differentiation.»

During her postdoctoral work, Bissell noticed that removing mammary cells from a mouse and putting them into a culture dish caused them to lose not only their normal in vivo shapes, but also their ability to secrete milk.

«The concentrations of anabasine tested here are 100-fold lower than those required to inhibit growth of parasite cell cultures,» Palmer - Young says, «and we did not find any evidence for variation in anabasine sensitivity across parasite strains.

They found that when IGF - 1 was added to the cultured blood cells there was increased lithium sensitivity only in the blood cells of those bipolar disorder patients who did not respond to lithium therapy.

We were able to use pharmaceuticals to induce cell self - eating effects and stimulate dedifferentiation though not as effectively as 3D culture, so we need to do more work on this.

2 - D cell - culture and mouse experiments also provided key evidence of the virus's modus operandi; although the rodent brain doesn't harbor the full contingent of human neural stem cells, it has blood vessels and immune - system components that organoids lack.

«This pilot study showed that the culture system not only allowed for efficient propagation of sperm stem cells, but also eliminated ALL cells,» said Sadri - Ardekani.

But the transition from brain - cell cultures to the brains of intact animals does not seem to bode well for astronaut resilience.

They noticed that while the dermal papilla cells from mice naturally formed large clumps in culture, the human cells didn't.

Studies of IBD are typically performed using cell culture experiments or animal models, which don't mimic the precise conditions that occur in the gut of human patients.

In cells grown on flat culture dishes, the expression of thousands of genes didn't match up with their normal patterns, explaining why the cells from those dishes had been unable to generate new hair follicles.

But boys who haven't been through puberty can only have sperm stem cells removed and frozen in anticipation of technology that could culture the cells and place them back in the testes, where they produce sperm after puberty.

(Although Clevers's organoids originate from adult stem cells, isolating those cells isn't necessary; culturing a tissue fragment with the right nutrients is enough.)

Existing cell culture models were not very realistic, Tuveson says, and creating genetically engineered mice took up to a year, compared with up to 3 weeks for pancreatic cancer organoids.

«Five years later,» Daley said, «I still don't know of any laboratory that has been able to culture those cells.

Around the same time, Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan, cultured the first brain organoids, starting not with adult stem cells but with embryonic stem cells.

«To do that, we went back to the cell culture model to ask whether or not the antibody basically prevents the uptake of misfolded α - syn.»

In practice, however, lung cells — especially from older, ill patients — won't grow well enough in culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she says.

The research showed the beta - lactamase genes in Klebsiella pneumoniae were on all the time, whether or not the bacteria were infecting human cell cultures.

The research highlights the importance of studying the effects of drugs not only on the tumor cells in a culture plate, but also on the interaction of the tumor cells with their own microenvironment.

They must not fixate on simply achieving a technical tour de force of cell culture in bioreactors.

This is the reason why haploid cell cultures do not thrive.

Cell culture systems used today also do not faithfully represent the features of human neurons.»

Researchers could identify which individual cells — from a tumor or a strain of bacteria — survive a drug treatment and study them further, something that's not possible with current culture - and - stain tests, Demirci says.

Kass developed the midstream urine test (still used when you pee in a cup) and set a numerical cutoff for the number of bacteria in normal urine: not more than 100,000 colony - forming units (cell clusters on a culture dish) per milliliter of urine.

«We're seeing that some of these factors have a major impact on cell behavior that is not possible to observe in conventional 2D cell cultures.»

«Until now, retention of salivary gland cell properties has not been possible using other tissue culture techniques.

Investigations into human brain development using human cells in the culture dish have so far been very limited: the cells in the dish grow flat, so they do not display any three - dimensional structure.