High intake of marine ϖ - 3 polyunsaturated fatty acids (PUFAs) is associated with lower risk of microsatellite instable (MSI) colorectal cancers (CRCs) but
not microsatellite stable (MSS) CRCs, according to a new study published March 25 in the JNCI: Journal of the National Cancer Institute.
Not exact matches
Microsatellites are a gene mapper's dream:
not only are they repeated different numbers of times in different people, but they are scattered throughout the genome.
Where the mitochondrial DNA that Georgiadis analyzed provides just a single locus for comparison, Wasser's team compared up to 16 loci in each
microsatellite sample — and the regional differences they found did
not evaporate upon closer inspection.
Analysis of polymorphic
microsatellites showed that the regions flanking COLQ are IBD, whereas those flanking the other 2 identified candidate genes are
not.
However, this node in the
microsatellite analysis is
not well supported with a bootstrap value of 49.6 %.