Yet despite the transformative impact on structural studies, it takes months to produce specifically tailored
nanobodies by llama immunization.
Not exact matches
The authors conclude «in summary, the development of chitosan nanoparticles loaded with current trypanocidal drugs coated
by a specific
nanobody against trypanosomes can reduce the minimal curative dose of these drugs, enhancing their efficacy, minimizing the toxicity and circumventing resistance mechanisms caused
by mutations in surface transporters.»
Figure 2: Condensin subunit SMC4 tagged with mEGFP and
nanobody - stained in a prometaphase HeLa cell visualised
by an astigmatic 3D STORM microscope.
Pleiner et al. have done the hard work for you
by immunizing an alpaca, isolating HCab antibodies from its serum, and meticulously screening, optimizing, and characterizing several anti-mouse and - rabbit
nanobodies.
Caussinus, E., Kanca, O., and Affolter, M. «Fluorescent fusion protein knockout mediated
by anti-GFP
nanobody.»