Sentences with phrase «nanocosmos at atomic resolution»

In 1990, Henderson was the first to use an electron microscope to produce «a three - dimensional image of a protein at atomic resolution.

Researchers have gone on to study «proteins that cause antibiotic resistance» and to produce three - dimensional images of the Zika virus at atomic resolution, permitting scientists to hunt for weaknesses that new pharmaceuticals could exploit.

«Additionally, while previous studies of dynein have revealed the molecule's two different static conformations, our animation visually depicts one plausible way that the protein can transition between those shapes at atomic resolution, which is something that other simulations can't do.

Then in 1990, after 15 years» work refining sample preparation and electron detection, Henderson succeeded in using an electron microscope to create an image of a large bacterial cell membrane protein called bacteriorhodopsin, and do it at atomic resolution.

The study appeared in the April 14 print edition of Chemical Communications in the article «Visualizing Nanoparticle Mobility in Liquid at Atomic Resolution,» by Madeline Dukes, an applications scientist at Protochips Inc. in Raleigh, N.C.; Benjamin Jacobs, an applications scientist at Protochips; David Morgan, assistant manager of the Cryo - Transmission Electron Microscopy Facility at Indiana University Bloomington; Harshad Hegde, a computer scientist at the Virginia Tech Carilion Research Institute; and Kelly, who is also an assistant professor of biological sciences in the College of Science at Virginia Tech.

On page 206 of this issue, Han et al. report images of halogen bonding at atomic resolution (4).

That work triggered a close race between the Cambridge University group and a rival team at MIT in deciphering tRNA's 3D structure at atomic resolution with x-ray crystallography, with the two labs publishing results within 2 weeks of each other.

«When combined with previous work, it is remarkable now to be able to assemble a true molecular movie of the photocycle of this blue light detector in bacteria at atomic resolution, with the intermediate structures appearing and fading in the correct sequence.

«Alzheimer fibrils at atomic resolution: Fundamental structural difference to earlier models.»

A European research team and a team from the United States (Massachussetts Institute of Technology in cooperation with Lund University) have simultaneously succeeded in elucidating the structure of the most disease - relevant beta - amyloid peptide 1 - 42 fibrils at atomic resolution.

This was made possible by a combination of nuclear magnetic resonance spectroscopy (NMR) and electron paramagnetic resonance spectroscopy (EPR), two procedures that make it possible to characterise the structural configuration of a protein at atomic resolution.

For example, he co-invented a widely used technique for locating impurity atoms in nanocrystals and published the first observation of dislocation kinks, at atomic resolution.

X-ray crystallography allowed scientists to «see» the structure of matter — whether it was molecular or otherwise — at atomic resolution.

It is powerful because an AFM can generate images at atomic resolution with angstrom scale resolution height information, with minimum sample preparation.

Twelve years later, he and his team succeeded in developing the NMR techniques for capturing a molecule in action, morphing into different shapes at atomic resolution.

Several more researchers presented their work during the day, including protein synthesis at atomic resolution, bio-imaging opportunities at synchrotrons, multi-dimensional imaging during plant cell differentiation, how to use electron cryomicroscopy for in situ structural biology, and how structured illumination microscopy can offer insights into the regulation of mammalian meiosis.

The final outcome is a detailed 3D view of the molecular structures at atomic resolution.

«Fitzpatrick and colleagues have paved the way for development of new drugs designed to prevent tangle formation by deciphering the molecular structure of the «tau» protein filaments that make up the tangles at atomic resolution.

«Seeing this drug bound to its intended human protein target at atomic resolution was mind - blowing,» said Frost, an assistant professor of biochemistry and biophysics at UCSF.

GERBER: Our sole idea in developing AFM was to image nonconductive surfaces, such as ceramics or biological materials, at atomic resolution by scratching a very fine needle on a long arm, or cantilever, over that surface.

Not exact matches

The resulting atomic - resolution topographic images reveal positions and orientations of atoms and molecules, and also provide a detailed look at structural defects in the surface.

Atomistic models and atomic - resolution STEM HAADF (scanning transmission electron microscopic high - angle annular dark - field) images showing three examples of segregation - induced superstructures observed at randomly - selected general grain boundaries of a nickel - bismuth (Ni - Bi) polycrystalline alloy.

The probe of an atomic force microscope (AFM) scans a surface to reveal details at a resolution 1,000 times greater than that of an optical microscope.

«Understanding how the enzyme actually works requires the knowledge of its three dimensional molecular structure at the atomic level,» said Dr. Mueller, principal investigator for the study that used cryo - electron microscopy (cryo - EM) to reveal the enzyme at near atomic resolution.

While cryo - EM isn't new, advancements in technology have made it possible to solve the structure at near atomic resolution.

Cryo - electron microscopy fires electrons at proteins that have been frozen in solution, providing images of such high resolution that scientists can create models down to the atomic level.

Shim and his research team combined X-ray techniques in the synchrotron radiation facility at the U.S. Department of Energy's National Labs and atomic resolution electron microscopy at ASU to determine what causes unusual flow patterns in rocks that lie 600 miles and more deep within the Earth.

Using this method, the biological molecules» three - dimensional structure can be determined at a nearly atomic resolution.

Until now, scientists couldn't examine dendrites so closely because the only technique for imaging battery components with atomic - level resolution destroys these fragile filaments, explains study coauthor Yuzhang Li, a materials scientist at Stanford University.

The first included pictures of individual nanoparticles» atomic structures at 100,000 - times magnification — the highest resolution images ever taken of nanoparticles in a liquid environment.

Now a team led by x-ray crystallographer Wayne Hendrickson at Columbia University in New York City and molecular virologist Joseph Sodroski at the Dana - Farber Cancer Institute in Boston has determined gp120's atomic structure to a resolution of 2.5 angstroms.

Taking this as his basis, he used x-ray diffraction experiments to elucidate its spatial structure at the level of atomic resolution.

At Cornell University, we developed and tested a new detector for electron microscopes that enables quantitative measurements of electric and magnetic fields from micrometers down to atomic resolution.

LiWang's lab also collaborates with X-ray crystallographers like Carrie Partch at the University of California, Santa Cruz, because X-ray crystallography is a powerful technique to capture static structures of proteins and their complexes at atomic and near - atomic resolution.

«Magnetism has its origins at the atomic scale, but the techniques that we use to measure it usually have spatial resolutions that are way larger than one atom,» Idrobo said.

Scientists are providing the clearest view yet of an intact bacterial microcompartment, revealing at atomic - level resolution the structure and assembly of the organelle's protein shell.

The researchers used electron cryomicroscopy and computer reconstruction techniques to visualize the channel at near - atomic resolution.

«The advantage of this system is that, potentially, it could cost only hundreds of pounds and gives resolution at the atomic scale,» says Peter Ivey, who is leading the team at the electrical engineering department in Sheffield.

I am an experimentalist, and I use ultrahigh - resolution ion - and electron - microscopy techniques, including focused - ion - beam scanning - electron microscopy and transmission electron microscopy, to determine the composition and structure of these materials at scales ranging from millimeters down to the atomic.

The microscope captures 3D images about once per second at resolutions of about 200 to 250 nanometers, not atomic resolution, but still at a dynamic level never before seen.

While there are very good bioinformatics tools for the analysis, validation and comparison of detailed atomic structures, at present there are very few tools available to work with low - resolution data (i.e. volume or shape data).

Platinum atomic signal was monitored at 265.945 nm, and increased peak resolution was adjusted with 12 points per peak.

Kamal Youcef - Toumi, a professor of mechanical engineering at MIT and SASTA's Board member, says the instrument's sensitivity and speed will enable scientists to watch atomic - sized processes play out as high - resolution «movies.»

Join us on October 10th to learn about SPHIRE (SParx for HIgh Resolution Electron microscopy) from Toshio Moriya, post-doctoral fellow at the Max Planck Institute of Molecular Physiology SPHIRE: User - friendly pipeline for near - atomic...

«I was very excited to see the electron density map and how you can determine the structure at near atomic resolution,» Dong says.