Sentences with word «nanomolar»

Successful approaches in structural manipulation led to a number of compounds with antiviral activities in the low nanomolar range and acceptable pharmacokinetic properties.
And plenty of other animals have a different array of receptors, Li says, from chickens that also lack the sweet gene to catfish that can detect amino acids in water at nanomolar concentrations.
For stable, yet reversible protein immobilization we have developed tris (nitrilotriacetic acid)(tris - NTA), which binds oligohististidine - tagged proteins with nanomolar affinity due to multivalent interactions (1, 2).
After affinity maturation, two of the designed proteins, HB36 and HB80, bind H1 and H5 HAs with low nanomolar affinity.
Early results show effective dosages at nanomolar concentrations.
They identified 24 molecules with nanomolar potency against both parasites, 30 molecules causing delayed death (in toxoplasma), out of which three interfere with apicoplast segregation, an essential process for the formation of new daughter cells.
EOS100850 potently inhibits A2A receptor in T lymphocytes, at single digit nanomolar concentrations, independently of adenosine concentrations
Chemotype Evolution has identified nanomolar inhibitors of kinases and protein - protein interactions starting from molecules with micromolar to millimolar potency.
Statins are HMGR inhibitors with inhibition constant values in the nanomolar range that effectively lower serum cholesterol levels and are widely prescribed in the treatment of hypercholesterolemia.
The team from JGU's Institute of Physical Chemistry used four different target proteins to demonstrate the viability of the new concept, its ability to detect concentrations in the nanomolar range, and the possibility to recycle the sensors for more than one analysis.
Both conjugates were obtained in very high yield and demonstrated strong tumor inhibition activity in a nanomolar range on Gb3 - positive cells.
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