(2010)
Nanoparticle Drug Delivery to Retinal Ganglion Cells in Glaucoma (Investigative Ophthalmology & Visual Science, 51: ARVO E-Abstract 3167).
An illustration from the Benoit lab shows how it forms
nanoparticle drug delivery vehicles.
This research report on global
nanoparticle drug delivery market provides an in - depth analysis of the market with special emphasis on the global market size, current market trends, dynamics and other factors that might have an impact on the market.
Her clinical - minded approach to laboratory research has recently led her to join forces with immunologists at the Indian Institute of Technology (IIT) in Bombay on a project that will explore how the immune system reacts to
nanoparticle drug delivery... -LSB-...]
Prior studies suggested that
nanoparticle drug delivery might improve the therapeutic response to anticancer drugs and allow the simultaneous monitoring of drug uptake by tumors.
«Furthermore, the use of particles to create these microswimmers will synergize well with other micro - and nanoparticle based technologies such as
nanoparticle drug delivery systems.»
It covers areas such as
nanoparticle drug delivery and possible future applications of molecular nanotechnology (MNT) and nanovaccinology.
Fast forward 2 years: Gray is working as a postdoc in the lab of USC oncology researcher Michael Wong, on
a nanoparticle drug delivery system.
• Oculis, an Iceland - based developer of a solubilizing
nanoparticle drug delivery platform, has raised an undisclosed amount of Series A funding co-led by Brunner Ventures and Silfuberg.
Not exact matches
The method involves tagging a molecular
drug delivery vehicle with synthetic DNA that can then be used to see how cancerous tumors are responding to specific treatments (the
drugs themselves are placed into these tagged
nanoparticles).
Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the genetic sequence of a protein or studying targeted
drug delivery by using magnetic
nanoparticles — is available from federal funding and foundations.
«Now that we have a more complete understanding of this stability, we can better tailor the
nanoparticle morphologies and in turn properties, to applications from biolabeling of individual cells and targeted
drug delivery to catalytic reactions, thereby creating more efficient and sustainable production processes.»
«We envision that these photo - responsive polymer - capped gold
nanoparticles could one day serve as nano - carriers for
drug delivery into the body using our robust and reversible process for assembly and disassembly,» said Zhiqun Lin, a professor in the Georgia Tech School of Materials Science and Engineering.
But Moderna's newer
drugs don't have those problems, he says, thanks in part to a careful redesign of their
delivery vehicle, the lipid
nanoparticle.
«The ability to identify useful
drug delivery nanoparticles using this miniaturized system holds great potential for accelerating our discovery process,» Anderson says.
Dr. McCabe said
nanoparticles are a leading - edge technology also being studied for
delivery of
drugs for other conditions, such as cancer, heart disease, and bacterial infections, in order to target specific cells to reduce toxicity and side effects of those medications and to make them more effective.
While researchers have long worked with
nanoparticles for
drug delivery, the findings put forth by He and his team represent a crucial breakthrough in addressing multidrug resistance in cancer cells.
The technique can be applied in myriad ways, some of which include droplet - based microreactors (devices used in chemical synthesis),
nanoparticle synthesis, tissue engineering,
drug discovery and
drug delivery monitoring.
Magnet - directed
nanoparticles have previously been used for targeted
delivery of chemotherapy
drugs.
Khizroev used the tail - to - head trick to spread the
nanoparticles through the brain and mimic IV
drug delivery in humans.
His research group will also work on targeted
delivery of the
drug using their patent pending «nanobowls,» which are magnetically guided
nanoparticles that can be packed with
drugs and diagnostic molecules, deliver them to particular sites in the body and release them on demand.
«
Nanoparticles combine photodynamic and molecular therapies against pancreatic cancer: Novel
drug -
delivery system cuts off common treatment escape pathways in animal models.»
The paper has «really intriguing results,» says Joseph DeSimone, a chemist and
nanoparticle and
drug delivery expert at the University of North Carolina, Chapel Hill.
A
nanoparticle drug -
delivery system that combines two complementary types of anticancer treatment could improve outcomes for patients with pancreatic cancer and other highly treatment - resistant tumors while decreasing toxicity.
iRGD is therefore potentially useful to optimize the
delivery of cancer
drugs by the
nanoparticle to the tumor.
Knudsen speculates that one of the attributes that makes positive micelles and similar
nanoparticles such powerful
drug delivery systems may also be what is causing the brain damage.
While on one hand, there is significant potential in the application of
nanoparticles in enhancing heat transfer for tumor ablation and targeted
drug delivery, there is also much promise in improving imaging and diagnostic protocols using them.
Nanoparticles are ubiquitous in industrial applications ranging from
drug delivery and biomedical diagnostics to developing hydrophobic surfaces, lubricant additives and enhanced oil recovery solutions in petroleum fields.
And a few different techniques have since emerged to improve
drug delivery, and, by extension, safety — such as Alnylam's approach of binding the RNAi therapeutic to a lipid
nanoparticle, or fat, to help it settle in the liver.
Levy's
nanoparticles were just a curiosity until he tied them to a novel
drug -
delivery method.
«Breakthrough antimalarial
drug delivery system using mesoporous silica
nanoparticles.»
The
nanoparticles also have potential as safer targeted
drug delivery systems.
One of the hopes is that once nanotechnology is proved safe and effective as a
drug delivery system, highly concentrated
nanoparticles carrying
drugs could be injected directly into the body where they are needed most and use their shape to get to work quickly.
Drug delivery systems (DDS) such as lipid - or polymer - based
nanoparticles can be designed to improve the pharmacological and therapeutic properties of
drugs administered parenterally.
A new study shows that a 70 - year - old malaria
drug can block immune cells in the liver so
nanoparticles can arrive at their intended tumor site, overcoming a significant hurdle of targeted
drug delivery, according to a team of researchers led by Houston Methodist.
Using chloroquine, the researchers not only increased the circulation of
nanoparticles in the body, but also reduced the body's filtration of
nanoparticles, as well as improved
drug delivery to breast tumors.
«Age - old malaria treatment found to improve
nanoparticle delivery to tumors: Nanomedicine researchers find new use for 70 - year - old
drug.»
Protein - based
nanoparticles are ideal for
drug delivery because they are compatible with human biology, are biodegradable, and have low toxicity.
Winner: ToleRaM Nanotech LLC — developed as a platform to synthesize and market novel
delivery devices wherein antirejection
drugs are encapsulated in a biologically inert
nanoparticle device and delivered in a focused manner to a transplanted organ with triggered - release
Nanoparticles are being studied as
drug delivery systems to treat a wide variety of diseases.
Silk helps make bio-integrated electronics (May 2010) Silk protein fibroin - blended
nanoparticles for
drug delivery (Jan 2013)
To give the siRNA more staying power, the researchers developed a
drug delivery system in which polymer - based
nanoparticles carry siRNA to the site of the graft and slowly release the
drug.
Nanoparticles for the sole use of imaging agents have a much lower return on investment and higher safety requirements than
drug delivery systems... -LSB-...]
The qNano system was presented to Prof... I am very excited that qNano will help us in accelerating our translational efforts in
nanoparticle based
drug delivery for affordable therapies in cancers and other diseases worldwide.»
Apart from the various biomedical applications of nanomaterials, especially in cancer therapy, cellular uptake of
nanoparticles is a key factor in recent years for efficient
drug delivery applications.
Major challenges in the development of
drug delivery systems (DDSs) have been the short half - life... chemistry affects the PK profile and organ distribution of a gold
nanoparticle - based DDS containing both a passive and active targeting moiety via... -LSB-...]
Nanoparticles conjugated with two active ligands, one for its effective uptake and the other for it's binding or use to gene
delivery agents to deliver
drug inside cells.
Because of their unique properties such as monodispersity, large surface area and high
drug loading efficiency, silica
nanoparticles (SiNPs) have been developed for a vast array of biomedical uses such as optical imaging, cancer therapy, targeted
drug delivery and controlled
drug release for genes and proteins.
Research Paper Placenta - specific
drug delivery by trophoblast - targeted
nanoparticles in mice Baozhen Zhang, Lunbo Tan, Yan Yu, Baobei Wang, Zhilong Chen, Jinyu Han, Mengxia Li, Jie Chen, Tianxia Xiao, Balamurali K Ambati, Lintao Cai, Qing Yang, Nihar R Nayak, Jian Zhang, Xiujun Fan Theranostics 2018; 8 (10): 2765 - 2781.
April 12, 2018 - Increase in the adoption of these instruments has been observed in last few decades owing to increase in research and development activities in
nanoparticle based dosage form development and evolution of targeted
drug delivery system.