Sentences with phrase «nanoparticles carrying»

Nanoparticles carrying drugs or short interfering RNA have shown great potential for the treatment of a variety of diseases, including cancer.

One of the hopes is that once nanotechnology is proved safe and effective as a drug delivery system, highly concentrated nanoparticles carrying drugs could be injected directly into the body where they are needed most and use their shape to get to work quickly.

When the nanoparticles carrying the Cas9 mRNA strand were injected, the cells began producing the Cas9 protein, but only for a few days because the mRNA eventually degraded.

So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.

The nanoparticles carry a drug compound that blocks a protein called Myc that is active in many types of cancer, including multiple myeloma.

To give the siRNA more staying power, the researchers developed a drug delivery system in which polymer - based nanoparticles carry siRNA to the site of the graft and slowly release the drug.

MIT's new nanoparticle carries three cancer - fighting drug molecules — doxorubicin is red, the small green particles are camptothecin, and the larger green core contains cisplatin (Image: Jeremiah Johnson)

• Chameleons inspire mechanochromic photonic films (Nov 2017) • Magnetic nanoparticles carry DNA into flowering plants (Nov 2017) Solar energy research thrives in symbiosis (Oct 2017)

Not exact matches

BACTERIA - HUNTING VIRUSES Viruses (one illustrated, center) can be engineered to carry magnetic nanoparticles and modified DNA, transforming them into nanobots that detect bacteria in water or food.

For this study, Yanik's team developed a new technology to inject RNA carried by nanoparticles called lipidoids, previously designed by Daniel Anderson, an associate professor of chemical engineering, member of the Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science, and an author of the new paper.

«If nanoparticles are carrying a drug to deliver, different uptake could mean different therapeutic efficacy and other important differences, such as safety, in clinical data.»

Artist's conception of nanoparticle - carrying immune cells that target tumors and release drug - loaded nanoparticles for cancer treatment.

Lanza also designed the nanoparticles to carry targeting molecules that home in on and bind to cancer cells that carry the complementary receptor, like a lock and key.

Biodegradable plastic molecules (orange) self - assemble with DNA molecules (intertwined, black circles) to form tiny nanoparticles that can carry genes to cancer cells.

Working together, Johns Hopkins biomedical engineers and neurosurgeons report that they have created tiny, biodegradable «nanoparticles» able to carry DNA to brain cancer cells in mice.

When exposed to a magnetic field, injected magnetic nanoparticles heat up and cause neurons carrying a gene for heat sensitivity to fire (shown in yellow, white, green and light blue at right).

Vassaux's team next plans to test gene therapy carried by nanoparticles on a variety of tumors in animals.

«The nanoparticle is like a taxi carrying two important passengers,» Prof. Satchi - Fainaro continues.

MIT engineers designed RNA - carrying nanoparticles (red) that can be taken up by endothelial cells (stained blue).

The researchers from UGA and Clarkson University in New York first created very fine nanoparticles that acted as drug carriers, one a substrate base carrying the drugs, and the other loaded with enzymes.

To carry out the study, the team has analysed how different carbohydrates act on the surface of silver nanoparticles (Ag - NP) of around 50 nanometres, which have been introduced into cultures of liver cells and tumour cells from the nervous system of mice.

UCLA scientists have unlocked an important mechanism that allows chemotherapy - carrying nanoparticles — extremely small objects between 1 and 100 nanometers (a billionth of a meter)-- to directly access pancreatic cancer tumors, thereby improving the ability to kill cancer cells and hence leading to more effective treatment outcome of the disease.

For the past two decades, scientists have been developing nanoparticles made from a broad range of materials and adding compounds such as cholesterol to help carry these therapeutic agents into cells.

This nanoparticle — one - thousandth the width of a human hair — carries a load of a lethal chemical: docetaxel, which is currently used to treat prostate cancer.

One use for nanoparticles that is gaining momentum is their ability to carry prescription drugs.

«We haven't even begun to look at the full potential of what [nanoparticles] could carry.»

By varying properties such as charge, composition, and attached surface molecules, researchers can design nanoparticles to deliver medicine to specific body regions and cell types — and even to carry medicine into cells.

They found a way to block it using a nanoparticle - carried small interference RNA, which enables the skin to heal faster.

New technique detects target DNA (here, anthrax) by using it to link fixed strands with «probe» strands attached to current - carrying gold nanoparticles.

The nanoparticle, the vector for IL - 2, carries the substance to the receptors in cancer cells, then saturates them and kills them, besides generating an immune T cells bridge (in charge of activating the immune response of the organism).

The nanoparticle has interleukin 2 on its surface, so when the protein is around it acts as a switch, a contact with the cancer cell to bind to the receptor and to carry out its biological action.

The group that got F3 with the Photofrin - carrying nanoparticles came through the best: they lived for, on average, 33 days; three of the five in this grouping lived for 60 days, and two of those three appeared tumor - free after six months.

PEG - PLA nanoparticles have an inner core that is ideally suited to carry hydrophobic small - molecule drugs, which include many chemotherapy drugs.

The researchers designed the oral delivery system, which contains micro - and nanoparticles, to carry a protein therapy that treats hemophilia B.

It's the result of an effort by Paula Hammond, who heads MIT's chemical engineering department, to perfect a process of layer - by - layer assembly that enables nanoparticles to carry several drugs between their strata.

The team used nanoparticles to carry the CRISPR components, eliminating...

A new nanoparticle is capable of carrying cancer - fighting drugs to a tumor site in the lungs before releasing them (Image: Shutterstock)

Researchers at BWH developed the nanoparticles using biodegradable, FDA - approved polymers engineered to carry the healing, stabilizing anti-inflammatory peptides.

Scientists have developed drug - carrying nanoparticles capable of targeting cancer tissue in the lungs.

The approach, they say, could be expanded to allow a nanoparticle to carry hundreds more.

The researchers believe this approach can potentially be used to link hundreds of building blocks to create multidrug - carrying nanoparticles, and pave the way for entirely new types of cancer treatments, free from the damaging side effects that accompany traditional chemotherapy.

The approach, they say, could be expanded to allow a nanoparticle to carry hundreds more, paving the way for new types of cancer treatments.

«We think it's the first example of a nanoparticle that carries a precise ratio of three drugs and can release those drugs in response to three distinct triggering mechanisms,» says Johnson.

Increasing a nanoparticle's ability to carry more drugs expands treatment options, but creating nanoparticles capable of delivering more than one or two drugs has proven difficult — until now.

The nanoparticles, which degrade over time into harmless components, could one day carry life - saving drugs to patients suffering from dozens of health conditions, including cancer.

Biodegradable nanoparticles (orange) carry short - lived gene therapy to specific cells (light teal).

The extension to a much larger network of slime mold tubes could process nanoparticles and carry out sophisticated Boolean logic operations of the kind used by computer circuitry.

Stephan's nanoparticles also have the potential to help make current immunotherapies more effective by providing T cells with nanoparticle «backpacks» to carry the right mix of molecules that T cells need to survive and sustain a robust anti-cancer response.

In our bloodstream, the nanoparticles then bind to a protein in our blood called albumin as it gets carried around the body.

The black side of the microparticles carries not only a negative charge, but also a number of magnetic nanoparticles that are attracted to magnets pulled across the surface of the white display.