Sentences with phrase «nanoparticles only»

But injected nanoparticles only work near the spot they were injected — and they don't remain there for very long.

«This peptide acts as a «zip code» in that it enables the binding of the nanoparticles only to blood vessels within the tumor and not normal blood vessels,» says Alnawaz Rehemtulla, a radiologist and environmental health scientist who co-authored the study.

However, the nanoparticles only released their payload when they reacted with molecules on the tumour's surface, so up to 80 per cent less of the drug needed to be injected to get the same amount into the tumour.

Not exact matches

«It was only possible to compare our experimental results with computer simulations because we mixed nanoparticles whose behaviour we can control very well,» he said.

The company has a useful technique for incorporating nanoparticles into polymers, but with only about ten employees, it lacks the resources to pursue the many possible applications.

To address this challenge, our research group is using nanoparticles not only to deliver more chemotherapy drugs to the target site within cancer cells, but also to compromise the function of the efflux pumps and thereby significantly improve safety and efficacy of cancer therapy.»

Both gold and silver nanoparticles were tested, but only the silver ones were toxic to the fish embryos in all sizes, according to the study.

«We need to design nanoparticles that will, like a lock - and - key mechanism, travel through the body and interact only with the diseased cell surface,» says Marth.

«The difference in the strength of the force being measured is extraordinarily small,» said Arnold, who explained that the measured electrostatic force involved in keeping a nanoparticle in orbit was only 0.00000000000003 (3x10 - 14) pounds.

This research makes a significant advance on previous efforts that have typically produced nanoparticles limited to only three different elements and to structures that do not mix evenly.

This is largely because conventional nanoparticles interact only weakly with the applied field, so quite a large dose is needed to generate enough heat to damage the tumor.

«Using our new technique, we could not only see that individual nanoparticles showed different extents of reaction at a given time, but also how the reaction worked its way through the interior of each nanoparticle,» Cabana said.

The binder performs several tasks here: it not only makes the TCO nanoparticles adhere well on the film; it also increases the flexibility of the TCO coating: in this way, the conductivity is maintained even when the films are bent.

That means one would need to give only 10 % of the original dose to patients to achieve the same degree of hyperthermia as with traditional nanoparticles.

And because they are only 2 to 8 nanometers in diameter, they are easy for the kidneys to clear from the body before they block up blood vessels, a long - standing problem in nanoparticle therapy.

The tiny nanoparticles used for catalysis often consist of only a few platinum atoms.

When the nanoparticles carrying the Cas9 mRNA strand were injected, the cells began producing the Cas9 protein, but only for a few days because the mRNA eventually degraded.

This basic principle predicts that the only shape of nanoparticles can be spherical or close - to - spherical ones.

Silver nanoparticles are not only used to make homemade remedies; they are also increasingly used in drugs such as vaccines, as well as products such as clothes and cleaning cloths.

The core nanoparticle, only 13 nanometers in diameter, enters cells, and the NanoFlare seeks its target.

There are currently people who use silver nanoparticles to make homemade potions to combat infections and illnesses such as cancer and AIDS, although in some cases the only thing they achieve is argyria or blue - tinged skin.

«We have observed that it is only when silver nanoparticles enter inside the cells that they produce serious harm, and that their toxicity is basically due to the oxidative stress they create,» explained the chemist Guillermo Orts - Gil, project co-ordinator.

In this case, it means identifying a material that bonds only with cement nanoparticles and nothing else in the cement.

Researchers are interested not only in which nanoparticles deliver the therapeutics most effectively, but also which can deliver them selectively to specific organs.

Until now, however, the only reliable way to make gold nanoparticles was to combine the gold precursor chloroauric acid with a reducing agent such as sodium borohydride.

Only nontoxic nanoparticles can be screened, and researchers must control for potential inflammation generated by the inserted DNA.

In a four - year study conducted on the mouse model in advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kill.

Duke University researchers have developed tiny nanoparticles that help convert carbon dioxide into methane using only ultraviolet light as an energy source.

This strategy led to the discovery of NIR luminescence and also paves the way for other types of nanoparticle alloys that are useful not only in imaging, but in applications like catalysis for the industrial - scale conversion of fossil fuels into fine chemicals.

The research, in which the CIC biomaGUNE and the Universidad Politécnica de Madrid also participate, not only represents a record in optical quality in which billions of gold nanoparticles behave as a single one, but introduces a new way to manipulate and improve nanomaterials by employing lasers as chisels in the hands of a sculptor.

«What we have shown is that nanoparticles of inorganic materials, just like the organic materials like early amino acids, can not only self - assemble, but can do so in a way that exhibits chirality,» said Nicholas Kotov, the Joseph B. and Florence V. Cejka Professor of Engineering and a professor of chemical engineering, materials science and engineering and molecular science and engineering at U-M.

Hochella and his team found these previously unknown nanoparticles not only in coal ash from around the world and in the gaseous waste emissions of coal plants, but on city streets, in soils and storm water ponds, and at wastewater treatment plants.

Scientists have only the broadest suspicions about harm that nanoparticles may cause.

In experiments with mice, the nanoparticle - based therapy not only wiped out the original targeted breast cancer tumors, but metastases in other parts of the body as well.

Analyzing the data using a sophisticated model developed at MIT, the researchers discovered that only a small percentage of nanoparticles absorbed and released ions during charging, even when it was done very rapidly.

By synthesizing a nanoparticle that releases its siRNA cargo only after it enters targeted cells, Dr. Tariq M. Rana and colleagues showed in mice that they could deliver drugs that silenced the genes they wanted.

«New nanoparticle that only attacks cervical cancer cells.»

Those molds were only 0.04 inch (one millimeter) square and yielded very few nanoparticles of controlled size and shape.

The binder performs several tasks here: it not only makes the TCO nanoparticles adhere well on the substrate; it also increases the flexibility of the TCO coating: in this way, the conductivity is maintained even when the films are bent.

Even then, the procedure only captures a small fraction of the nanoparticles present in the biological fluid.

This treatment depends on only sunlight for energy, and the nanoparticles can be recovered and reused indefinitely.

Now, researchers from the University of Waterloo have developed a topical solution containing nanoparticles that will combat dry eye syndrome with only one application a week.

These kinds of observations can not be easily made under a microscope, of course, but require instead an indirect, statistical approach: «Using small - angle X-ray scattering at BESSY II, we were not only able to ascertain that the nanoparticles are all around five nanometres in diameter, but also measure what the separations between them are.

The nanoparticles, about 1 / 1000th the width of a human hair, stick harmlessly to the eye's surface and use only five per cent of the drug normally required.

The findings are significant, because the nanoparticles not only remained in circulation, but also accumulated in mouse tumors, as well as in the lungs of healthy mice, suggesting that the approach also may enhance treatment for lung diseases.

Some scientists have had minor successes getting intravenous drugs past the barrier with the help of ultrasound or in the form of nanoparticles, but those methods can target only small areas.

«We know, however, that these kinds of small clusters of nanoparticles are especially effective as catalysts for chemical reactions we want: a many-fold increase in the reaction speed due only to particle arrangement has already been demonstrated,» says Rademann.

Using chloroquine, the researchers not only increased the circulation of nanoparticles in the body, but also reduced the body's filtration of nanoparticles, as well as improved drug delivery to breast tumors.

Even in nanomedicine, which is one of the best new methods for delivering drugs to a tumor, only about one percent of a dose of nanoparticles will successfully arrive at the intended tumor site, while the rest are filtered out by the immune cells of the liver and spleen.

Especially exciting is that Prof. Sowwan and his team that includes scientists from Ireland, Greece, India, United Kingdom, Peru, South Korea, Palestine, France, Spain, and Japan, can customize not only the shape and structure of the nanoparticles but also the nanoparticles» characteristics.