Sentences with phrase «nanoparticles through»

Increasing the stiffness of cancer cell membrane enhanced the entry of polymer nanoparticles through pathways rich in cholesterol.
«Previously, we've delivered nanoparticles through the bloodstream and shown that they inhibit inflammation in a model of rheumatoid arthritis.
A magnet pulled «smart» nanoparticles through a mouse's bloodstream into its brain, similar to this figure.
Khizroev used the tail - to - head trick to spread the nanoparticles through the brain and mimic IV drug delivery in humans.
a) Gold nanoparticle catalyst (Au / HAP - NC), b) Images of gold nanoparticles (black dot in red circle) through Transmission Electron Microscope, c) Annular Dark Field of gold nanoparticles through Scanning Electron Microscope.

Not exact matches

To get around this gatekeeper, researchers have tried a number of approaches — including attaching drugs to nanoparticles that might slip through the BBB.
, is funded through a National Science Foundation CAREER award and bridges previous research focused on designing nanoparticles for catalytic applications.
By including chemotherapy molecules in the nanoparticle structures when they are assembled, the molecules could be drawn into tumors — and then released with the application of a light at a shorter wavelength that triggers disassembly through photo - cleavage.
Beyond the activity of the drugs, the plasmonic effects of the gold nanoparticles could heat the nanoparticles when they are subjected to light, attacking the cancer cells through a second route.
These materials are sensitive to light, and cause the nanoparticles to self - assemble through a photo - dimerization process — crosslinking — when subjected to light at a wavelength of 365 nanometers.
When two spherical nanoparticles collide, energy dissipates around the initial point of contact on each one instead of propagating all the way through both.
It also enables the nanoparticle size to be tightly controlled, which is important when trying to block some wavelengths of light while allowing others to pass through.
Nanoparticles likely enter the environment through wastewater, where they accumulate in biosolids (sewage sludge) at wastewater treatment plants.
They'll also work with materials scientists to create a reproduction that mirrors the composition of different - shaped nanoparticles to see how they navigate through the bloodstream so the team can run virtual tests of new treatments in nanomedicine.
«We need to design nanoparticles that will, like a lock - and - key mechanism, travel through the body and interact only with the diseased cell surface,» says Marth.
The nanoparticle, according to the scientists, helps the drug slip through capillaries near cancer cells and remain within the tumor longer than it would otherwise.
«With this force in hand both the charge on the nanoparticle and the microcavity charge density could be calculated through a series of experiments.»
«Using our new technique, we could not only see that individual nanoparticles showed different extents of reaction at a given time, but also how the reaction worked its way through the interior of each nanoparticle,» Cabana said.
They injected the nanoparticles into a mouse's bloodstream through its tail.
Once the nanoparticles squeezed through the barrier and the mouse was exposed to a weak magnetic field, the critter's brain responded by firing electrical signals.
In testing with hydrogen peroxide, a strong oxidizing agent, the researchers found their most effective cerium oxide III nanoparticles performed nine times better than a common antioxidant, Trolox, at first exposure, and held up well through 20 redox cycles.
«Through nanocharges it is possible to add other properties to the intrinsic properties of the basic materials: nanoparticles, nanoclays, fibres, etc..
HST researchers have experimented with polymer - coated iron oxide nanoparticles held together by DNA tethers to help them create a visual image of a tumor through magnetic resonance imaging.
«We addressed this challenge through the controlled, multiscale assembly of nanoparticles by leveraging the kinetics of polymer crystallization.»
«We have been developing the expertise required to grow intricate core / shell and other well defined nanoparticles for many years,» Vela said, «Through our collaboration with Emily Smith's group, we hope to continue making inroads in our ability to manipulate and direct energy flows at the nanoscale.»
Reactants can flow into the hollow structure through holes in the faces, interacting with more platinum atoms in the chemical reaction than would be the case on a flat sheet of platinum or traditional, nonhollowed nanoparticles.
However, if a voltage is applied from one side of the film to the other, electrons can pass from one layer of gold to the next by burrowing through the cadmium sulfide nanoparticles in between.
A new technique invented at MIT can measure the relative positions of tiny particles as they flow through a fluidic channel, potentially offering an easy way to monitor the assembly of nanoparticles, or to study how mass is distributed within a cell.
They also reproduced the «cleaning» effect of nanoparticles, which go through in lymph nodes, by «washing» lymph off them and reinjecting them into the blood serum.
He then placed small amounts of the charcoal - colored nanoparticles into a reaction chamber and passed mixtures of carbon dioxide and hydrogen through the powdery material.
It can also keep nanoparticles from clumping together, so they spread widely through a liquid.
In this research, which has yet to be published, the nanoparticles would be injected instead of applied topically, so that they could circulate through the bloodstream and slowly release their nitric oxide payload.
Hoffmann began working with nanoparticle semiconductors through his academic and professional career.
«Potentially harmful nanoparticles produced through burning coal: Environmental scientists led by the Virginia Tech College of Science have discovered that the burning of coal produces incredibly small airborne particles of a highly unusual form of titanium oxide with the potential to be toxic to humans.»
Meanwhile, Glotzer's group has championed the role of nanoparticle shape in guiding the assembly of crystal structures through computer simulation.
In 1996, he introduced the concept of using nanoparticles as atoms and synthetic DNA — the blueprint of life — as a chemically programmable bond to make designer materials based upon the ability of the particles to recognize one another through sequences immobilized on their surfaces.
Mirkin's group has pioneered many structures through the use of DNA strands as a sort of smart glue, linking nanoparticles together in a particular way.
But the authors say further attention should be given to nanoparticles to which humans are directly exposed, through the air or the skin.
The group that got F3 with the Photofrin - carrying nanoparticles came through the best: they lived for, on average, 33 days; three of the five in this grouping lived for 60 days, and two of those three appeared tumor - free after six months.
But the independent report, issued by the Royal Society and the Royal Academy of Engineering on Thursday, recommends that «free» nanoparticles, or those that could come into direct contact with humans through the air or the skin, be subject to fresh regulatory controls.
The drug is a spray of nanoparticles, which are small enough to be absorbed through the lungs» air sacs and into the bloodstream.
The nanoparticles collide to produce scatterings of light, like sun streaming through clouds, doing away with the need for bulky mirrors.
Melander's team, which is not involved in any of DeSimone's work, is currently testing their gold nanoparticles» ability to cross through a simulation of the blood — brain barrier that prevents many substances from passing into the brain from the bloodstream.
The device sends a tiny amount of silver nanoparticle tracers in rapid pulses through a solid column, simulating the much longer path the particles would travel in a well.
When ingested, nanoparticles pass into the blood and lymph system, circulate through the body and reach potentially sensitive sites such as the spleen, brain, liver and heart.
Barenholz's nanoparticles generally stayed in the bloodstream and avoided the heart and other organs, but when they reached the leaky blood vessels in the tumor, they slipped through those holes.
Any large molecules floating outside the cell — such as RNA, proteins or nanoparticles — can slide through the membrane during this disruption.
To show that the enzymes were trapped inside the FMS pores, the team stained the protein - FMS complex with gold nanoparticles and documented the enzyme - in - pore complex through electron microscopy.
Light can be used to activate normal, non-genetically modified neurons through the use of targeted gold nanoparticles, report scientists from the University of Chicago and the University of Illinois at Chicago.
A nanometre is 1 billionth of a metre, hence nanoparticles are small enough to move through the bloodstream.
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