Sentences with phrase «narcolepsy in»

This is the source of the exhibition's title, «Narcolepsy in Pink.»

Travis Collinson has been featured in group exhibition throughout the country most recently in Look at me: Portraiture from Manet to Present at Leila Heller Gallery in New York and a solo exhibition at Dominican University titled Narcolepsy in Pink.

There are two forms of narcolepsy in dogs.

Narcolepsy in dogs presents as excessive fatigue, lethargy and brief losses of consciousness.

Attacks of narcolepsy in dogs and of cataplexy in dogs are both sudden in onset, they typically last from a few seconds to a few minutes, and they resolve spontaneously.

Amphetamines are also present in some medications used for weight loss and narcolepsy in humans.

For a sport that induces rabid obsession in its fans and narcolepsy in its detractors, there have been a startling number of well made, and totally different, movies about baseball.

Professor Mignot is internationally renowned for having discovered the mutation that causes narcolepsy in dogs.

And it may be that the vaccine only accelerated progression of narcolepsy in children who would have developed it anyway.

When they heard about the rise in narcolepsy in 2010, neuroscientist Lawrence Steinman of Stanford University in Palo Alto, California, and rheumatologist Sohail Ahmed, who at the time was global head of clinical sciences at Novartis's vaccines and diagnostics division in Siena, Italy, began scouring databases for proteins expressed in the brain that might resemble those in the vaccine.

The work strongly suggests that Pandemrix, which was given to more than 30 million Europeans, triggered an autoimmune re action that led to narcolepsy in some people who are genetically at risk.

That knowledge, coupled with evidence that narcolepsy in humans might be an autoimmune disorder, has led many researchers to suspect that sufferers have immune systems that are genetically predisposed to attack and destroy hypocretin - producing cells.

Not exact matches

Besides Xyrem, Jazz has a handful of sleep drugs in late - stage development, including one that has been submitted to the Food and Drug Administration for approval to treat narcolepsy and obstructed sleep apnea.

The investors are frustrated that shares in Jazz, a $ 9 billion pharmaceutical company known for its narcolepsy drug Xyrem, have remained essentially flat over the past year.

Mary could not receive the «power of the Spirit»; Deborah could no longer cry, «Give ear, you princes» (nor could she sing of the «warriors in Israel unbinding their hair,» lest baldness carry moral reproach); and the report in Acts that «with these words, [Stephen] fell asleep» would need correction out of deference to those afflicted by either narcolepsy or insomnia.

Narcolepsy — this toddler sleep disorder have a great difficulty in getting up in the mornings.

My first benefitted immensely from bed sharing, and being a new mom with narcolepsy, I felt that the extra sleep I got once I gave in to what felt natural, bed sharing, was safer than falling asleep inadvertently when holding the baby and nursing or sitting.

Interestingly, those who suffer from narcolepsy, a disease in which people are excessively tired and may spontaneously fall asleep during the day, also lack orexin due to a breakdown in the brain cells that produce it.

Dr. Saper's research has explored circuitry of the brain that controls basic functions such as wake - sleep cycles, feeding, and immune response, and how these circuits are disrupted in neurological disorders, such as Parkinson's disease, in sleep disorders such as narcolepsy and sleep apnea, and during aging.

Similar mutations, it turned out, appear in both Doberman pinschers and Labrador retrievers bred for narcolepsy.

The hypocretin receptor 2 gene could be the single most important gene in human narcolepsy, says Michael Aldrich, a neurologist and director of the University of Michigan's Sleep Disorders Center.

These drugs may be used recreationally to purposefully alter one's consciousness (such as coffee, alcohol or cannabis), as entheogens for spiritual purposes (such as the mescaline - containing peyote cactus or psilocybin - containing mushrooms), and also as medication (such as the use of narcotics in controlling pain, stimulants to treat narcolepsy and attention disorders, as well as anti-depressants and anti-psychotics for treating neurological and psychiatric illnesses).

Mutations in the orexin receptors are associated with narcolepsy, a chronic sleep disorder.

Henry Nicholls sets out to uncover the truth about his condition, only to find that drug companies are more interested in inducing narcolepsy than curing it

Of the $ 2,836,088 in «direct public support» the NSF received in 2005 (the most recent IRS disclosure I could find), it seems that $ 470,000 came from Pfizer, which in 2005 was primping for the debut of the sleep - aid drug Indiplon, which it has since dropped; $ 299,000 came from GlaxoSmithKline, makers of Sominex; $ 152,000 from King Pharmaceuticals (Sonata); $ 596,670 from Sanofi Aventis (Ambien); $ 471,800 from Takeda Pharmaceuticals (Rozerem); $ 133,183 from Sepracor (Lunesta); $ 100,000 from the hepcats over at Jazz Pharmaceuticals, who make the narcolepsy drug Xyrem; and $ 100,000 from Cephalon, maker of another drug used for narcolepsy, Provigil.

The cells are crucial for arousal during sleep - wake cycles and are thought to play a key role in narcolepsy.

The visitors, members of a narcolepsy support group from California's East Bay area, laughed, then caught themselves and awww - ed in sympathy.

What we call narcolepsy was first noted by French physician Jean - Baptiste Edouard Gelineau in the 1880s.

Narcolepsy usually shows itself during adolescence or in the early twenties, «a really tough time,» Mignot notes.

Although narcolepsy appears to be genetically based in humans, simply having the defective gene doesn't mean a person will have the disorder.

As a lab researcher with a Ph.D. in molecular pharmacology, he believes he has finally discovered the key to understanding — and maybe someday curing — narcolepsy.

Mignot's purpose in occasionally inviting people with narcolepsy to meet Beau is to give them hope.

He came to the United States in 1986 to test a French narcolepsy drug on the Stanford sleep center's colony of narcoleptic dogs, mostly Doberman pinschers and a handful of Labrador retrievers and dachshunds bred for the disorder.

Optogenetics also has been used to mimic the underlying mechanisms in narcolepsy, a disorder that causes patients to fall asleep at inopportune times.

Previous research suggests exposure to a virus may elicit a similar reaction in genetically predisposed people, leading to narcolepsy.

That knowledge in turn promises to pave the way for more precise treatments and stronger relief from narcolepsy's debilitating symptoms.

However, children in northern Europe who received adjuvanted flu vaccines in 2009 had slightly higher rates of narcolepsy than normal.

Meanwhile, pharmaceutical companies are racing to design new narcolepsy drugs based on the discovery of hypocretin's central role in the disorder.

«It may be that a mild form of narcolepsy happens much more often than we realize and is an unappreciated cause of excessive sleepiness in the general population,» says Mignot.

The US is now funding a large study of countries that used adjuvanted vaccines in 2009 to see if they may have caused narcolepsy.

► Why did about 15,000 children in Europe develop narcolepsy after receiving the flu vaccine Pandemrix?

Although humans with narcolepsy do not possess the same genetic mutation, this finding still proved instrumental in unraveling the disease's fundamental cause.

In recent sleep lab studies of 600 people age 30 or older, Mignot was surprised to find that 1 percent — or 20 times as many as with classic narcolepsy — suffered from inordinate sleepiness, had a high frequency of the autoimmune marker linked to narcolepsy, and went very rapidly into REM when they napped.

Poertner has narcolepsy, a sleep disorder that affects between 25 and 50 people in 100,000.

In December, Outi Vaarala of the University of Helsinki and her colleagues had reported that Pandemrix contained a much higher level of nucleoprotein than a GSK vaccine called Arepanrix, which was associated with a much smaller risk for narcolepsy.

In patients with narcolepsy, their immune system destroys the hypocretin cells located in the brain, which are important in order for them to stay awakIn patients with narcolepsy, their immune system destroys the hypocretin cells located in the brain, which are important in order for them to stay awakin the brain, which are important in order for them to stay awakin order for them to stay awake.

Researchers suspect an autoimmune reaction is to blame because many people who develop narcolepsy — and just about everyone with the vaccine - associated form — have a specific variant in a gene in the HLA family, which helps the body distinguish its own proteins from those made by microbial invaders.

Cases of narcolepsy increased after the 2009 pandemic in China, where Pandemrix wasn't used, and researchers discovered that serum from some H1N1 influenza patients does bind to the hypo cretin receptor.

It turned out that, in some people with a specific genetic variant, the vaccine, Pandemrix, caused narcolepsy and this generated a lot of discussion as to whether other autoimmune diseases may be induced by the vaccine.

But the results still need to be confirmed in a larger study, the authors and other narcolepsy researchers say.