In the early 1980s, scientists at the University of Tokyo found that all of
their narcolepsy patients had the same form of the human leukocyte antigen, or HLA.
In the meantime, the new insights might eventually lead to ways to help
narcolepsy patients.
In the new work, the researchers added serum from Finnish
narcolepsy patients who had received Pandemrix to cells that were engineered to display human hypo cretin receptor 2 on their surface.
That was the big news at the Oct. 2010 «Annual
Narcolepsy Patient Conference» I attended was.
Not exact matches
Optogenetics also has been used to mimic the underlying mechanisms in
narcolepsy, a disorder that causes
patients to fall asleep at inopportune times.
In
patients with
narcolepsy, their immune system destroys the hypocretin cells located in the brain, which are important in order for them to stay awake.
Cases of
narcolepsy increased after the 2009 pandemic in China, where Pandemrix wasn't used, and researchers discovered that serum from some H1N1 influenza
patients does bind to the hypo cretin receptor.
In late 2013, he published what seemed to be a breakthrough study of
patients with
narcolepsy, which identified self - reactive T - cells that pursued the hormone hypocretin.
Through his work with large
patient groups, he has managed to show that
narcolepsy is closely genetically linked to so - called HLA molecules, which play a key part in the immune system by presenting foreign substances to immune cells.
While I do think I benefitted from entering into ketosis, I would not necessarily recommend a Ketogenic diet to
patients unless to achieve some sort of therapeutic goal, such as improved insulin resistance, or for adjunct cancer care, to reduce inflammation, or to improve severe depression, migraines, or
narcolepsy.