EFFECT: Decreased circulating androgens Male and female infertility: Decreased sperm production in males; fetal loss in females Genital malformations Cleft palate and various birth defects Immune suppression
Hyperkeratosis and other skin diseases Growth retardation Increased mortality
A deficiency of vitamin A can lead to rough, scaly skin,
hyperkeratosis pillaris (raised bumps usually on the back of the arms) and acne.
Thickened keratin or calluses, which is medically referred to as
hyperkeratosis, peels off of feet when this product is applied within four to six days.
In the future I will explore this with a full and detailed post that will enable you to sort out
hyperkeratosis for good.
For example, arsenic is an inflammatory heavy metal you need to avoid, and when you do so you will also tackle the problem of
hyperkeratosis.
When sebum oxidises, it causes a condition called
hyperkeratosis, which means that far too much keratin is produced.
Hyperkeratosis causes your dead skin cells to stick together, form massive clumps and then get lodged firmly in your pores.
Furthermore, footpad
hyperkeratosis as recently been confirmed as a genetic disorder.
Idiopathic digital
hyperkeratosis usually occurs in dogs older than 10.
Digital
hyperkeratosis is a «frustrating disease to manage,» according to the McKeever Veterinary Dermatology Clinics website.
However, in August 2008 Professor Tosso Lieb and a team of geneticists at the University of Berne, in conjunction with ANTAGENE, started a research project to analyse the genomes of a number of breeds of dog (including the Irish terrier, but not the Bedlington terrier) in which footpad
hyperkeratosis was a problem.
«I am contacting you to let you know that we have performed a study to look at Hereditary Footpad
Hyperkeratosis in the Bedlington Terrier.
The end result of the research was that there was a common gene mutation that was responsible for footpad
hyperkeratosis in all the breeds involved in the research project.
Other dogs develop
hyperkeratosis, or abnormal, hard skin growths on the footpads and nose.
The Health Group felt that the statement in relation to «feet» used in Breed Watch documentation was too general and did not reflect the nature of the problem (Footpad
Hyperkeratosis) in Bedlington terriers and, incidentally, in Irish terriers.
References DVM 360: Localized Keratinization Syndromes (Proceedings) Animal Dermatology Clinic of British Columbia: Paw and Nail Disorders McKeever Dermatology Clinics: Nasal and Digital
Hyperkeratosis petMD: Inflammatory Skin Disease in Dogs Vetstream: Skin — Keratinization disorders University of Prince Edward Island: What is Seborrhea?
Labrador retrievers particularly are prone to nasal
hyperkeratosis.
Older dogs might develop nasal
hyperkeratosis, a nose condition resulting when dead skin stops sloughing off.
Hereditary footpad
hyperkeratosis is an autosomal recessive skin condition found in certain breeds of dogs in which the foot pads become hardened, losing their normal elasticity, developing painful cracks that are prone to infections that can lead to lameness.
Digital
hyperkeratosis: a condition of Irish terrier puppies that causes marked thickening of the foot pads.
Even puppies that recover may suffer from longer term effects of the disease, such as tooth decay (enamel hypoplasia) and hardening of the foot pads and nose (canine
hyperkeratosis).
Signs of a vitamin A deficiency in cats are similar to those in other species, except that classic xerophthalmia, follicular
hyperkeratosis, and retinal degeneration are rarely seen and usually are associated with concomitant protein deficiency.
The first is a condition which affects the nose and feet, called Nasodigital
Hyperkeratosis, in which the keratin in the nose and paw pads develops into a tough, fibrous growth — often resembling callusing.
Although
hyperkeratosis can't be cured, it can be controlled.
Nasodigital
hyperkeratosis is a disorder characterized by excessive growth of the epithelium of the nose and footpads.
In
hyperkeratosis, keratin - the tough, fibrous outer covering of foot pads - grows excessively.
In some cases,
hyperkeratosis of the nose and footpads may be seen (the nose and footpads become very thickened and cracked — see photo).
(Kennel Club Press Release) The Kennel Club has approved a new official DNA testing scheme for Hereditary Footpad
Hyperkeratosis (HFH) in Irish Terriers, following consultation with breed clubs.
We have had quite good success treating corns with creams prepared for human use for conditions such as ichthyosis and
hyperkeratosis.
Hyperkeratosis is also known as hairy dog feet.
There may be an underlying cause as to why your dog has
hyperkeratosis...
Typical signs of canine distemper seen in the domestic dog include respiratory and intestinal problems such as coughing, diarrhoea, vomiting, nasal and ocular discharge, anorexia, and
hyperkeratosis of the nasal planum and foot pads.
Cutaneous lesions include
hyperkeratosis, follicular keratosis, hyperpigmentation, adnexal atrophy, loss of elastin fibers, and a loose network of collagen fibers in the dermis.
In some dogs there may be a genetic predisposition to
hyperkeratosis.
Hyperkeratosis of foot pads and nasal surfaces can also be associated with other medical conditions.
Without overt evidence of other illnesses, though, most cases of
hyperkeratosis require skin biopsies that are then evaluated along with your dog's breed information, history and physical findings.
Treatment and management of
hyperkeratosis As you might imagine, the management of your dog's
hyperkeratosis depends on the specific cause; so the diagnosis is an important step.
What is canine
hyperkeratosis?
Testing for
hyperkeratosis Typically dogs with underlying infectious and immune mediated diseases will have other lesions and / or illness that will lead your veterinarian to suspect these conditions as the cause of your dog's
hyperkeratosis.