«Cancer hijacks
natural cell process to survive.»
Cancer tumours manipulate
a natural cell process to promote their survival suggesting that controlling this mechanism could stop progress of the disease, according to new research led by the University of Oxford.
Not exact matches
Molecular biology, contrary to the article, does not support evolution by
natural chance because evolution can not occur without inheritance, inheritance can not occur without DNA and DNA is so complex it could not have evolved by chance unless we are to assume that molecules just happened to arrange themselves into the DNA molecule at the same times as a nucleus formed to hold the DNA, at the same time as the
cell membrane just happened to form around it, at the sametime as all the
cell maintaining
process in the cytoplasm just happened to come into existence to form a single
cell and that all these aspects just happened to come together and work harmoniously.
If, on the other hand, we define evolution in the Darwinian sense — as a
process of random mutation and
natural selection by which all living beings have arisen by chance from single -
celled organisms over 100's of millions of years — we may not be on equally firm ground from a scientific perspective.
Cell replication allows our bodies to grow and develop, yet can result in cancer when
natural processes misfire.
The body wears out, mutations accumulate faster than can be repaired just through the
natural process of
cell division, cancer grows, arthritis wracks the world worn joints, the child born with tetralogy of Fallot away from surgical care dies.
For now, drugs such as rituximab that deplete B -
cells not only offer potential relief for those with autoimmune illnesses, but a new way of understanding these conditions — as an unintended consequence of the
natural selection
process B -
cells undergo each time they encounter a new pathogen.
This
natural selection
process results in a B -
cell that binds almost perfectly.
The technology offers unprecedented views of cellular
processes and will allow researchers to observe
cells in their
natural state, an important step in teasing out normal and disease
processes.
TOUGH STUFF A new wood - compacting
process crushes the gaps between
cell walls in
natural wood (porous structure seen in the scanning electron microscopy image, left), making the densified wood (right) as strong as steel.
Combing the genetic data from a transmission study in ferrets, a team led by Thomas Friedrich, a professor of pathobiological sciences at the University of Wisconsin - Madison School of Veterinary Medicine, found that during transmission, when one animal is infected by another through sneezing or coughing, the
process of
natural selection acts strongly on hemagglutinin, the structure the virus uses to attach to and infect host
cells.
Furthermore, it has been shown that the body's
natural process of healing the wound created by surgery can actually spur these residual cancer
cells to metastasize to distant parts of the body and form new growths.
After deciphering this
natural differentiation
process, the investigators duplicated it in the laboratory dish by adding a sequence of proteins, called growth factors, to the fluid bathing the stem
cells.
But Whitehead Institute researchers have found a mechanism underlying this resistance — a mechanism that naturally occurs in many diverse cancer types and that may expose vulnerabilities to drugs that spur the
natural cell - death
process.
The vaccine harnesses the
natural process of T -
cell immunity to tumors, but enhances it to help overcome tumors» formidable defenses.
In this
process, several hundred times more
cells of the so - called myeloid lineage (thrombocytes, erythrocytes, granulocytes, monocytes) form than long - lived lymphocytes (T
cells, B
cells,
natural killer
cells) do.
But it is never clear by what
process these
cells are formed or how similar they are to the
natural versions.
Programmed
cell death, or apoptosis, is a
natural process that kills billions of
cells in a typical human body each day.
Proteins called kinesins, for example, are
natural nanomotors that support cellular functions such as mitosis (the chromosomal
process that creates two nuclei from one parent nucleus) and meiosis (when the number of chromosomes per
cell is reduced by one half).
The
natural structures that exist either between
cells or within
cells are damaged during the freeze - thaw
process and hence the flavor or texture of the tissue is altered.
One of the genes that MM41 blocks — the BCL - 2 gene — is involved in regulating apoptosis, the body's
natural process which forces
cells to die if they become too damaged or unhealthy to be repaired.
That viral DNA is then directly spliced into the host
cell's DNA and passed along with the
cell's
natural replication
process.
Jon Tilly, the director of the Vincent Center for Reproductive Biology at Massachusetts General Hospital in Boston, has been studying genetically altered mice to better understand the
process of apoptosis, or
natural cell death.
Using photolithography and re-flow
processing, Abadi's substrates are patterned at the micron and submicron levels, approximating the
natural physical forces
cells experience.
Fuel
cells can run on hydrogen,
natural gas, or biofuels — the latter two requiring a reformer that
processes the fuel to extract hydrogen.
The presence of these abnormal circuits may also inhibit the
natural process of removal of unnecessary developing brain
cells known as pruning.
The challenge was to find the right balance of light and dark, given that yeast
cells die when their
natural fermentation
process is disturbed, Zhao said: «The yeast get sick.
Telomeres are caps on the ends of chromosomes that shorten as
cells replicate — part of the
natural aging
process.
However, the dengue virus uses this
natural process to its advantage: the
cells that recognize the constant region of an antibody are the exact
cells dengue virus prefers to infect.
The sugar enhances a
natural cholesterol - removal
process and persuades immune
cells to soothe inflammation instead of provoking it, say immunologist Eicke Latz and colleagues.
Using the
natural human development
process as a guide, the researchers developed ways to mature muscle
cells in the laboratory to create muscle fibers that restore dystrophin, the protein that is missing in the muscles of boys with Duchenne.
The drug, known as HRX9, works by preventing the cancer
cells from avoiding apoptosis — the
natural process by which unhealthy and damaged
cells close themselves down and die.
The Bag1 gene, for example, codes for a protein that in humans is involved in inhibiting an essential
natural process called «programmed
cell death.»
To assemble the largest pieces of DNA, they inserted them into yeast
cells and exploited a
natural process called «homologous recombination,» which is used by yeast to repair damaged DNA.
Traditional hydrogels made up of either synthetic polymers or
natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological
processes, such as
cell / tissue development.
Therefore, the walls of this
cell could be studied without having to inhibit it from its
natural processes.
A
natural process called nonsense - mediated decay, or NMD, provides
cells with the ability to detect errors in the coded RNA messages, called transcripts, that are copied from DNA when genes are activated.
One of these T
cell subsets is comprised of the CD1d - reactive invariant
natural killer T
cells, and over the years we have studied the development, homeostasis, activation and regulation of function of these
cells, as well as their specificity and the pathways leading to the
processing and presentation of antigens by CD1d.
They instead seem to be a product of
natural selection, optimized to generate a favorable degree of genetic diversity, as well as to help safeguard the organism's
cells against the kinds of errors that tend to occur most frequently during the
process of protein synthesis.
For nearly 20 years, the scientists painstakingly worked out how to add two new custom - made letters to the genome's
natural four - letter vocabulary, integrate them into the
cell and synchronize a complex series of
processes to make that expanded vocabulary meaningful.
They began by inducing both embryonic stems
cells and iPS to morph into a form of embryonic tissue that — in a
natural process — gives rise to blood stem
cells.
Nanostructured and chemically functionalized materials which mimic architectural and mechanical features of
natural cell microenvironments hold promise for a better understanding and control of
cell physiological
processes through molecular and nanoscale interactions.
TRAIL is a
natural antitumor protein that suppresses tumor development during immune surveillance, the immune system's
process of patrolling the body for cancer
cells.
Allogeneic
cell therapies involving primary
cell types such as bone marrow mesenchymal stromal / stem
cells (BM - MSCs), hematopoietic stem and progenitor
cells (HSPCs), and T and
natural killer (NK)
cells for immunotherapy applications are especially challenging because of the vigorous
process of screening...
The
process, known as differentiation, attempts to replicate in the lab the
natural development of neurons from undifferentiated stem
cells in a human embryo.
This confirms the vital role of «developmental engineering,» in which
natural processes are mimicked to control the development and specification of adult stem and progenitor
cells.
They're too slow to study
natural three - dimensional (3D) cellular
processes in real time and in detail (the sharpest views have been limited to isolated
cells immobilized on glass slides).
PROVIDENCE, R.I. [Brown University]-- Scientists report in a new study that by imitating a
natural process of
cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Fawzi hypothesized that because phosphorylation is a
natural process of
cells, the key may be finding a «switch» to turn it on when needed.
It is always possible that a vector will introduce the gene into a
cell other than that for which it is supposed to be targeted (e.g., a spermatocytic
cell) or that through a secondary mechanism target
cells that have taken up the new gene will through some independent
natural process (such as transfection) transfer the gene to a germline
cell.