Sentences with phrase «natural signaling patterns»
Besides displaying more natural signaling patterns, 3D cultures allow researchers to mix cell types in ways that mimic their interactions in living tissue, providing more accurate models of normal physiology and pathogenesis.
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It is a natural unit functioning in an environment, and it maintains its patterned activities through responding to signals from outside.
RIKEN researchers have taken up this challenge, and the work published in Cell Reports details how sequentially applying several signaling molecules to three - dimensional cultures of human embryotic stem cells prompts the cells to differentiate into functioning cerebellar neurons that self - organize to form the proper dorsal / ventral patterning and multi-layer structure found in the natural developing cerebellum.
Nonetheless, even if the substantial recent trend in the AO pattern is simply a product of natural multidecadal variability in North Atlantic climate, it underscores the fact that western and southern Greenland is an extremely poor place to look, from a signal vs. noise point of view, for the large - scale polar amplification signature of anthropogenic surface warming.
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Nonetheless, even if the substantial recent trend in the AO pattern is simply a product of natural multidecadal variability in North Atlantic climate, it underscores the fact that western and southern Greenland is an extremely poor place to look, from a signal vs. noise point of view, for the large - scale polar amplification signature of anthropogenic surface warming.
To sum up, in my view the strength of the method of Hay et al. is that it uses the expected «fingerprints» of the global warming signal, while the strength of Church & White is to take into account the empirical patterns of natural variability.
On the other hand, it does not explicitly take into account the specific patterns of natural variability caused by winds or currents that can masquerade as a false global signal (as described above).
Both are observed fluctuations in mid-ocean temperatures in the Pacific that are the signal for changes in the climate pattern: both are natural, both occur as part of a cycle, and both can be traced back through human history.
He said, «The pattern over the last 100 years has been characterized by overall warming, with signals of natural climate variability.»
The space - time structure of natural climate variability needed to determine the optimal fingerprint pattern and the resultant signal - to - noise ratio of the detection variable is estimated from several multi-century control simulations with different CGCMs and from instrumental data over the last 136 y. Applying the combined greenhouse gas - plus - aerosol fingerprint in the same way as the greenhouse gas only fingerprint in a previous work, the recent 30 - y trends (1966 — 1995) of annual mean near surface temperature are again found to represent a significant climate change at the 97.5 % confidence level.