Further analysis showed that wild type HIV - 1 tends to integrate itself into or
near genes affecting CD4 + T cell activation and metabolism more frequently than does the mutant strain.
Not exact matches
The second was the existence in laboratory mice of a large mutation called an inversion that
affects several million nucleotides
near the KITLG
gene.
Functional analyses indicate that MFSD12 encodes a lysosomal protein that
affects melanogenesis in zebrafish and mice, and that mutations in melanocyte - specific regulatory regions
near DDB1 / TMEM138 correlate with expression of ultraviolet response
genes under selection in Eurasians.
While the promoter mutations were not
near known pancreatic cancer
genes, the team discovered that they
affected some of the same biological pathways inside cells.