Sentences with phrase «near genes for»

The other finding was of a variant near genes for several so - called semaphorins, proteins that guide developing nerve cells as they grow toward their final targets.

Not exact matches

Whether you think Zayner is a prophet or a crackpot, the point is that you should get ready for gene editing and gene therapy coming to a hospital near you.

The researchers found, for example, that extraversion was associated with variants in the gene WSCD2 and near gene PCDH15; neuroticism was associated with variants on chromosome 8p23.1 and gene L3MBTL2.

Analysis of a specific gene has now demonstrated that although bats live in air and dolphins in water, where sound travels five times faster, they independently evolved a near - identical gene that allows them to accept high - frequency sound in the ear — vital for sonar.

Barroso spent his first year at GSK's Biopharmaceuticals Centre of Excellence for Drug Discovery near London looking at the use of adenoviruses in gene - transfer therapy.

Near each Crispr sequence are genes for a variety of Cas (Crispr - associated) enzymes, including Cas9.

The trust now plans to increase its spending from $ 160 million to $ 325 million over 7 years at the Sanger Centre near Cambridge — Britain's main gene sequencing laboratory — for more painstaking efforts to sequence a third of the human genome by 2005.

Last summer, Hamer and his colleagues made worldwide headlines when they announced that a region near the tip of the X chromosome probably contained a gene or genes for homosexuality.

The new locus they have identified is near a cluster of genes which code for proteins called «glycophorins» that are involved in the malaria parasite's invasion of red blood cells.

For example, the Antarctic icefish, a pale, near - transparent inhabitant of the frigid South Atlantic Ocean, has not only lost its ancestors» power to make oxygen - binding red hemoglobin (which it does not need in the cold oxygen - rich waters) but the two genes that code for hemoglobin have also gone extinct: one has disappeared, and the other remains as a non-coding «molecular fossil,» a useless remnant that hints at past use but still resides in the icefish DFor example, the Antarctic icefish, a pale, near - transparent inhabitant of the frigid South Atlantic Ocean, has not only lost its ancestors» power to make oxygen - binding red hemoglobin (which it does not need in the cold oxygen - rich waters) but the two genes that code for hemoglobin have also gone extinct: one has disappeared, and the other remains as a non-coding «molecular fossil,» a useless remnant that hints at past use but still resides in the icefish Dfor hemoglobin have also gone extinct: one has disappeared, and the other remains as a non-coding «molecular fossil,» a useless remnant that hints at past use but still resides in the icefish DNA.

For example, the widespread but not universal ability to digest the milk sugar lactose in adulthood (lactose tolerance) has recently been shown to arise from any of several different mutations in and near the lactase gene.

For example, domestication had seemingly altered 13 places near a gene called SOX2, which helps maintain cells destined to become part of the nervous system.

He and Duke graduate student Lomax Boyd scanned the genomic databases and combed the scientific literature for enhancers that were different between humans and chimps and that were near genes that play a role in the brain.

A second set of problems is presented by tests, likely to be available in the near future, for carriers of the so - called breast cancer gene (see «Breast cancer: a lethal inheritance», this issue).

The mutation isn't in a region of the gene that codes for the SMARCAD1 protein; instead it's near a key splicing site that prevents SMARCAD1 from being made correctly, the researchers report today in The American Journal of Human Genetics.

As soon as the near completion of the human genome was announced, commentators played up the payoff of finding genes for all sorts of diseases.

However, for some mouse DNA losses the case may be different, as in the mm10 genomic background they mostly occurred near genes involved in developmental processes.

However, 15,627 CpG sites in / near ∼ 30 % of all genes exhibited differential methylation in adipose tissue from a case - control cohort of unrelated individuals, supporting a key role for epigenetic modifications in T2D patients.

«It's a timely reminder that when contemplating the scene of a crime, it is wise to look beyond those potential culprits standing nearest to the body, some of whom may well be innocent bystanders, and to look for «motive» amongst those who may be standing a little distance away,» Mark McCarthy of the University of Oxford, a researcher who has worked on the connection between obesity and the FTO gene, told National Geographic's Not Exactly Rocket Science.

«But for complex traits, association signals tend to be spread across most of the genome — including near many genes without an obvious connection to disease.»

To evaluate the global human methylome in adipose tissue, we calculated the average level of methylation for all sites divided into groups based on either their location in relation to the nearest gene (Fig. 2A) or the location in relation to CpG islands (Fig. 2B)(24).

As reported today in Nature, the team deleted ten limb enhancers near genes essential for limb development.

In this manuscript we evaluate the potential for microbiome characterization by sequencing of near - full length 16S rRNA gene region fragments using the Oxford Nanopore MinION (hereafter Nanopore) sequencing platform.

We report 6 new signals of association in or near HSPB7, TNXB, LRP12, LOC283335, SEPT9, and AKT2, and provide new replication evidence for a further 2 signals in EBF2 and NFKBIA Combining large whole - blood gene expression resources totaling 12 607 individuals, we investigated all novel and previously reported signals and identified 48 genes with evidence for involvement in blood pressure regulation that are significant in multiple resources.

For example, there are predisposing genes with near 100 % penetrance such as Huntington's Chorea (everyone with the predisposition will manifest the syndrome if they live long enough), while there are many other genes, which have a low penetrance.

Stewart discovered that the histone modifications that poise embryonic stem cell - specific genes for activation are also found on the histones near genes involved in regeneration, putting them into a ready - to - go state.

Authentic motor racing genes, competitive technology and a spectacular design — the near - series four - door CLA 45 AMG Racing Series high - performance Coupé is intended for the avidly followed race series with turbocharged 2.0 - litre cars.

To reduce the frequency of kinks, dogs with kinks or which have near relatives with kinks should be bred to mates that have full tails and are from families where kinked tails are not known to occur as the genes for kinking may be entirely separate from the NBT gene.

Auburn University College of Veterinary Medicine, UMass Medical School to test gene therapy treatment for Tay - Sachs and Sandhoff diseases Researchers at Auburn University College of Veterinary Medicine and UMass Medical School are nearing human clinical trials on a genetic therapy for two rare neurological diseases that are fatal to children.

In evaluating the hips of dogs genetically predisposed to dysplasia, certain factors could make the hips in the leg - extended radiographs appear worse, compared to another dog with presumably the same genes for hip joint construction, such as a littermate or a dog with otherwise near - identical genotype yet reared differently.

Metagenomic sequencing led to the recovery of its near - complete genome, revealing the genes necessary for hydrogenotrophic methanogenesis.