Sentences with phrase «near genes linked»
Of particular interest was that four of the 10 sites most strongly linked to the AOSI scores were located near genes linked to Prader - Willi syndrome, a genetic disorder that shares some behavioral symptoms with autism.
https://www.sciencedaily.com/ Not exact matches
After gene - typing about 3,000 people, Sturm found that how OCA2 is expressed — and how much pigment a person has — is strongly linked to three single nucleotide polymorphisms (SNPs), or single letter variations, in a DNA sequence near the OCA2 gene.
Although they have not been implicated directly in pancreatic function, genomewide association studies have linked the presence of a mutation near the genes to an impaired ability to properly manage fasting blood - glucose levels.
In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly - linked pair of single - letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn.
Currently and in the near future, resources such as the Kaiser Permanente Research Program on Genes, Environment and Health; the UK Biobank; the VA Million Veteran Program; and others are making available genetic data linked to comprehensive EHR - based clinical outcomes and traits on over a million people.
A link between genes near an individual's disrupted transcription factor binding sites and their phenotype data is established in this paper, in a further foray beyond the exome: http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004711.