Knox thinks this is because the stem cells require signals from
nearby nerve cells to start the maturation process, but the nerve cells also stop functioning when the gland tissue dies.
A compressed and herniated disk, in which the rubbery cushion between vertebrae impinges on and
irritates nearby nerves, is a major cause of low back pain that can radiate to the legs.
When it is herniated, the disc can impinge
on nearby nerves, resulting in severe or chronic pain.
When activated, microglia release a range of toxic compounds that can cause collateral damage to
nearby nerve cells.
When the soft structure in the disc is pushed out via the outer cover, it affected
the nearby nerves.