The phrase
"necessary cofactors" refers to substances that are essential for a specific process or reaction to occur. They are like helpers that support and enable the main action to happen. Without these cofactors, the process would not be able to take place successfully.
Full definition
I regularly recommend this special cocktail, rich
in necessary cofactors, to support and boost our mitochondrial health — your energy levels with thank you.
In MPnS, this glutamine molecule binds to iron,
a necessary cofactor for the production of methylphosphonate.
All
the necessary cofactors to produce cortisol are depleted and so cortisol levels drop.
Another issue would be vitamin C and / or copper deficiencies since these compounds are
necessary cofactors that work with Dopamine B - hydroxylase to convert dopamine to Nr.
Simply because zinc is
a necessary cofactor for the creation of retinol binding protein, the substance which transports all vitamin A around the body.
Also, it's important to take a calcium supplement with
the necessary cofactors for appropriate assimilation.
A full compliment of essential vitamins provides
the necessary cofactors for cellular development.