Not exact matches
2003 Chinese company Shenzhen SiBiono GeneTech gains approval for treating head and
neck cancer with Gendicine, a modified adenovirus carrying a tumour - suppressor
gene.
Specifically, data from the
Cancer Genome Atlas showed signatures of APOBEC3 - mediated mutations in the PIK3CA
gene of about 40 percent of HPV - positive head and
neck cancers, but only about 10 percent of HPV - negative head and
neck cancers.
Applying their technique to head and
neck cancers, they've discovered seven new tumor - suppressor
genes whose role in
cancer was previously unknown.
A section of a head and
neck tumor — red and green markers show the proliferation of
cancer stem cells — that formed when one of several newly characterized
genes, Myh9, was suppressed.
«New RNA interference technique finds seven
genes for head and
neck cancer.»
In back - to - back papers published online July 28 in Science, researchers from the Broad Institute, Dana - Farber
Cancer Institute, Johns Hopkins Kimmel Cancer Center, the University of Pittsburgh, and the University of Texas MD Anderson Cancer Center have confirmed genetic abnormalities previously suspected in head and neck cancer, including defects in the tumor suppressor gene known a
Cancer Institute, Johns Hopkins Kimmel
Cancer Center, the University of Pittsburgh, and the University of Texas MD Anderson Cancer Center have confirmed genetic abnormalities previously suspected in head and neck cancer, including defects in the tumor suppressor gene known a
Cancer Center, the University of Pittsburgh, and the University of Texas MD Anderson
Cancer Center have confirmed genetic abnormalities previously suspected in head and neck cancer, including defects in the tumor suppressor gene known a
Cancer Center have confirmed genetic abnormalities previously suspected in head and
neck cancer, including defects in the tumor suppressor gene known a
cancer, including defects in the tumor suppressor
gene known as p53.
Since then, however, other researchers have observed the same
gene fusion in a percentage of lung, esophageal, breast, head and
neck, cervical, and bladder
cancers, affecting tens of thousands of
cancer patients overall.
Scholar - in - Training Awards in the amount of $ 1,000 for her submitted abstract entitled, «Activator protein 2 alpha (AP2α)- targeted methylation and silencing of relevant
genes in head and
neck squamous cell carcinoma (HNSCC) pathogenesis» to be presented at platform session at the 100th Annual Meeting of the American Association for
Cancer Research, Denver, CO..
In some cases, a
gene can act as a growth promoter in
cancer, and in other cases, such as head and
neck cancer, the same
gene behaves as a growth suppressor,» said Kinzler.
The next step based on these novel head and
neck cancer discoveries, the scientists agree, is to tease out how the
genes function in normal cells, whether they form the lining of the larynx, pharynx, or another anatomical site affected by head and
neck cancer.
Through this process, the scientists were able to narrow their search and focus on the
genes that were both mutated in head and
neck cancer and hijacked by HPV.