The rate of heart attacks was lower in the biologic group, generating an adjusted hazard ratio of heart attacks of 0.61 in the tumor
necrosis factor group compared to the DMARD group.
Not exact matches
Michael Croft, Ph.D., and his team focus on a number of molecules that are members of the tumor
necrosis factor (TNF) and tumor
necrosis factor receptor (TNFR) family, a
group of proteins believed to play important roles in the ability of the immune system to guard the body against harmful microorganisms.
Liposuction did not significantly alter the insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter plasma concentrations of C - reactive protein, interleukin - 6, tumor
necrosis factor alpha, and adiponectin; and did not significantly affect other risk
factors for coronary heart disease (blood pressure and plasma glucose, insulin, and lipid concentrations) in either
group.
C3G significantly upregulated the glucose transporter 4 (Glut4) and downregulated RBP4 in the white adipose tissue, which is accompanied by downregulation of the inflammatory adipocytokines (monocyte chemoattractant protein - 1 and tumor
necrosis factor - alpha) in the white adipose tissue of the C3G
group.