Sentences with phrase «necrosis in»

Single, small, basophilic, intranuclear inclusion bodies are most common in areas of necrosis in the lung, liver, and kidneys; occasionally, they are seen as faintly acidophilic bodies located within the nuclear space.

Pet Poison Helpline (PPH) has discovered that xylitol, a sweetener which causes hypoglycemia and hepatic necrosis in dogs, is showing up in some very unexpected places.

Other symptoms that cluster are also indicative of a parvo infection, these include: a low white blood cell count, diarrhea with blood in it and evidence of necrosis in the intestinal lining.

Rats were fed genetically modified corn chow on a daily basis for two years and the results included an exponential increase in mammary tumors, kidney failture and liver necrosis in the rats who ate GMO food compared to their control counterparts.

It was hypothesized that silver toxicity, as manifested by liver necrosis in laboratory rats, was due to silver induced inhibition of the synthesis of the seleno - enzyme glutathione peroxidase.

Read about the monitoring of apoptosis and necrosis in real time using the CLARIOstar's ACU feature, that maintains the appropriate O2 and CO2 environment for cells, while the RealTime - GloTM Annexin V Apoptosis and Necrosis Assay measures cell death using luminescence and fluorescent signals.

Lethal toxin did not cause apoptosis or necrosis in MNK - 3 cells.

At the cellular level, L - arginine administration resulted in acinar cell necrosis in both WNIN / Gr - Ob and control rats.

Catalase abrogates ß - lapachone - induced PARP1 hyperactivation - directed programmed necrosis in NQO1 - positive breast cancers.

By depriving the cancer cells of the amino acid cystine, the researchers were able to trigger a form of cell death called necrosis in mouse models of the disease.

«It helps to prevent necrosis in your sample,» says Carden.

Not exact matches

The Orthodox Church said in a statement that the change in law was «a satanic deed» and would lead to «the destruction of social cohesion and the spiritual necrosis of man».

Researchers at NYU School of Medicine found that the value of the drug infliximab, marketed as Remicade, in both applications proceeds from its ability to block the contribution of the protein tumor - necrosis factor alpha, or TNF alpha, to problem - causing inflammation.

Plasma membrane integrity and the display of phosphatidylserine on the plasma membrane's extracellular face are both hallmarks of apoptosis, and are used in this kit to distinguish apoptosis from necrosis.

The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.

In contrast, men have greater tumor necrosis factor - alpha, homocysteine and uric acid levels as well as higher coronary artery calcium score than women.

For 5 years, Beckmann was engrossed in many research projects, including an investigation of tumor necrosis factor receptors (TNFRs).

According to Dr. Schwarz, «We observed acute proinflammatory changes, namely, leukocytosis, neutrophilia, upregulated levels of IL - 6 in serum, and enhanced messenger RNA expression of IL - 6 and tumor necrosis factor alpha.

But two cytokines — interleukin - 17 (IL - 17) and tumor necrosis factor (TNF)-- are overexpressed in psoriasis, leading the immune system to attack a person's own skin cells.

The rate of heart attacks was lower in the biologic group, generating an adjusted hazard ratio of heart attacks of 0.61 in the tumor necrosis factor group compared to the DMARD group.

«Using tumor necrosis factor inhibitors decreases risk of heart attacks in rheumatoid arthritis patients.»

Taken together, this suggests that SRP - 6 protects worm cells against lysosome rupture and necrosis, the scientists conclude in the 21 September issue of Cell.

These little catfish will die in there, and that causes necrosis and rotting.

The sudden death of worms in room - temperature water has helped scientists identify a regulator of necrosis, a common form of cell death.

The researchers determined that the children with otulipenia might respond to drugs that turned off tumor necrosis factor, a chemical messenger involved in systemic inflammation.

One project that AquaGen started up in 2005 was a collaboration with the Centre for Integrative Genetics (CIGENE), at the Norwegian University of Life Sciences, and the Norwegian Institute of Food, Fisheries and Aquaculture Research (Nofima) to make a precise map of the genetic markers that make certain salmon individuals resistant to the IPN (infectious pancreatic necrosis) virus.

To produce a medical implant, we need to select materials with similar mechanical properties to those in biological tissues, so as to mitigate inflammation or necrosis.

In a previous study published in 2012, researchers treated psoriasis patients with antibodies that attack IL - 17A and with a substance, called an antagonist, that acts against tumour necrosis factor, another cytokine strongly implicated in psoriasiIn a previous study published in 2012, researchers treated psoriasis patients with antibodies that attack IL - 17A and with a substance, called an antagonist, that acts against tumour necrosis factor, another cytokine strongly implicated in psoriasiin 2012, researchers treated psoriasis patients with antibodies that attack IL - 17A and with a substance, called an antagonist, that acts against tumour necrosis factor, another cytokine strongly implicated in psoriasiin psoriasis.

The present study revealed that juvenile aseptic bone necrosis — a disorder in which poor blood supply leads to bone damage — might have rendered Tut particularly vulnerable to physical injuries.

In 2012, Dr. Krolewski and his team made a very important discovery when they found a link between tumor necrosis factor receptor 1 (TNFR1) and declining renal function in type 1 and type 2 diabeteIn 2012, Dr. Krolewski and his team made a very important discovery when they found a link between tumor necrosis factor receptor 1 (TNFR1) and declining renal function in type 1 and type 2 diabetein type 1 and type 2 diabetes.

Reactivation of HBV may occur with chemotherapy, organ and tissue transplantation, High dose corticosteroids, and biologicals targeting tumor necrosis factor - alpha (TNF - α), Anti-TNF medications are used in treating rheumatic diseases, such as rheumatoid arthritis, digestive conditions that include Crohn's and colitis, and dermatologic conditions, such as psoriasis.

In contrast to necrosis, which is a form of cell death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process that generally confers advantages during an organism's life cyclIn contrast to necrosis, which is a form of cell death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process that generally confers advantages during an organism's life cyclin a regulated process that generally confers advantages during an organism's life cycle.

Infliximab reduces symptoms and inflammation by targeting one of the proteins — called tumor necrosis factor (TNF)-- that leads to inflammation in IBD.

Such is the case for a DNA letter in the gene that encodes the protein called tumour necrosis factor receptor 1 (TNFR1).

The protein senses a potent immune molecule called tumour necrosis factor (TNF) that destroys cancerous cells but that is also implicated in autoimmune disease.

Researchers in Sweden sought to determine if use of tumor necrosis factor inhibitor drugs to treat RA would result in a reduced risk of acute coronary syndrome (commonly called ACS), defined as a diagnosis of a heart attack or unstable angina (the worsening or increasing cardiac symptoms)

Reports included in the bibliography indicate that some cancers regressed after they outgrew their blood supply and underwent necrosis, or tissue death.

Tumor necrosis factor inhibitor drugs (commonly called Anti-TNFs) modestly reduce the risk of acute coronary syndrome, such as heart attacks and angina, in rheumatoid arthritis patients whose inflammation places them at higher risk of developing coronary heart disease, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

«MRI is a unique tool for studying heart tissue that enables us to explore in exquisite detail heart function, necrosis, the state of the microcirculation, and many other parameters that are critical in determining the post-infarction status of the myocardium,» says Dr. Fuster.

«This finding was quite tantalizing given the fact that mutations in the NUP62 protein were shown by other researchers to cause an infantile form of Huntington's disease called infantile bilateral striatal necrosis,» says Grima.

Researchers led by David Wallach of the Weizmann Institute of Science in Rehovot looked more closely at a receptor called p55, which binds to a suicide - promoting cytokine called tumour necrosis factor (TNF).

Researchers from Massachusetts Eye and Ear / Harvard Medical School have identified inflammatory factors that cause optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro)-- similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the development of optic nerve damage in a mouse model.

They have detected, for example, revved up signaling molecules involved in inflammation, such as tumor necrosis factor α (TNFα) and other cytokines; skewed populations of natural killer cells and other immune cells; imbalances in the protein - destroying enzymes called proteases; and a shortening of the telomeres, the «end caps» on chromosomes, which indicates prematurely aged cells.

They found that microglia then responded to another protein found in the brain called ψ - interferon by producing free radicals containing nitrogen and a third protein called α - tumour necrosis factor.

In the process they induce inflammation; the cells also secrete other inflammatory chemicals, like interleukin - 6 and tumor necrosis factor - alpha, which are known to adhere to the endothelium of the blood vessels, an early event in atherosclerosiIn the process they induce inflammation; the cells also secrete other inflammatory chemicals, like interleukin - 6 and tumor necrosis factor - alpha, which are known to adhere to the endothelium of the blood vessels, an early event in atherosclerosiin atherosclerosis.

Across multiple triple - negative breast cancer subtypes, inhibiting the androgen receptor greatly increased apoptosis (programmed cell death), inhibited growth and increased necrosis by 60 percent in animal models.

«There's a specific pathologic phenomenon that we're seeing, which is acute tubular necrosis — acute damage to the tubules to the kidney associated with or in conjunction with these pretty characteristic [round] crystals that we're seeing in the animals» kidneys and urine,» he says.

A critical next step for this work is to understand how senescent changes in late life trigger such destructive waves of cellular necrosis.

Such necrosis is important in the meat industry, as it leads to meat tenderization; this is why hunters hang dead rabbits and pheasants for several days prior to cooking.

Four also had extensive liver necrosis, and two had cancer — leukemia in one case, lung cancer in the other.