Infection with Bb led to many histopathologic findings in infected animals not treated with dexamethasone, such as leptomeningitis, vasculitis, focal inflammation in the brain and spinal cord, and
necrotizing focal neurodegeneration and demyelination in the cervical spinal cord.
In dogs that succumb to the disease pathological examination of the liver often shows severe hepatitis (centrilobular hepatitis), inflammation of the arteries (multi
focal necrotizing arteritis) and kidney inflammation (membranoproliferative glomerulonephritis) as well as inflammation of the lymph nodes (lymphadenopathy)