«These results support advancing to a larger trial capable of addressing whether inosine might fill the critical unmet
need for disease - modifying treatment.
These results confirmed that Rett syndrome is an X-linked dominant disorder, meaning that only one bad copy of MECP2 is
needed for the disease to be fully penetrant.
These special funds focus attention and support on addressing the unmet patient
need for the diseases that have afflicted these heroic people.
Therefore, better treatments are urgently
needed for these diseases.
For the OCR A Level Geography specification, this series of handouts covers the content
needed for the Disease Dilemmas topic - Section 3: How effectively are communicable and non-communicable diseases dealt with?
For the OCR A Level Geography specification, this series of handouts covers the content
needed for the Disease Dilemmas topic - Section 3: How effe...
A community with no free - roaming cats equals a community with less injury to wildlife, less
need for disease control, fewer cats in need of interventions and more resources to be allocated elsewhere.
For example, the presence of physical symptoms, such as pain and fatigue, combined with
the need for disease management regimes, are likely to interfere with many aspects of daily life, such as regular school attendance and maintaining peer relations, and may cause frustration (e.g., Suris, Michaud, & Viner, 2004).
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential
for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences
for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals
for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand
for air travel or our operations from the outbreak of
diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price
for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate
for our additional capital
needs or
for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions
for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
Omada's digital therapeutics platform attempts to address disparate health care
needs that can be particularly cumbersome
for people at risk
for chronic
diseases like diabetes through a combination of data analytics, user engagement, and the broad goal of preventing these kinds of conditions from developing in the first place.
Last weekend, Scott sharply criticized the federal government and lawmakers
for dragging their feet in providing resources
needed to combat the
disease, including 10,000 Zika preparedness kits, mosquito spray and additional manpower to root out the mosquitoes.
As Americans live longer, debilitating
diseases such as Parkinson's and Alzheimer's are rising, making the
need for long - term care vital.
However, at that point, whether they had contracted any kind of contagious «moon
disease» was still up
for grabs, hence the
need for a quarantine shortly after their arrival.
The most important thing the international community can do is eliminate infected crops, and
for this to be realistic, scientists
need to invent a new diagnostic test that can very quickly detect the
disease in plantations and at quarantine borders.
«People
need help with navigating the system, like case management, finding housing, and help
for simultaneous chronic
diseases like cardiovascular
disease.»
That number needn't be so low, as many carriers offer online programs to help identify risk factors
for common chronic
diseases (e.g.: diabetes, congestive heart failure, asthma, obesity, cancer) and offer prevention programs.
While we all
need it, over a third of American adults aren't getting enough, according to the Centers
for Disease Control and Prevention (CDC).
Dr. Park Kisoo, a spokesperson
for the Korea Centers
for Disease Control and Prevention, discussed the
need for thorough personal hygiene at a press conference on Wednesday.
Through talking to experts in the field over the past year, Gates said he had identified five areas of
need: Understanding better how Alzheimer's unfolds, detecting and diagnosing it earlier, pursuing multiple approaches to trying to halt the
disease, making it easier
for people to take part in clinical trials of potential new medicines, and using data better.
Minoryx is a clinical stage biotech company leading the development of new therapies
for X-linked Adrenoleukodystrophy (X-ALD) and other inborn errors of metabolism, a group of rare
diseases of genetic origin with a high unmet medical
need.
For a government investing in health care and senior's care, it might be Deborah, the sandwich - generation single mom whose son has a rare
disease and whose mother
needs home - care service.
Keep reading
for more
need to know information about women and heart
disease.
By giving each individual patient control over their schedule, Namaste Alzheimer Center encourages dignity and care that is tailored
for the distinctive
needs of this
disease.
Fast track designation is granted to drugs that are
for serious or life - threatening
diseases and that the FDA believes demonstrate the potential to address unmet medical
needs.
By: Marleny Arnoldi 26th January 2018
For operational sustainability in the mining industry, mining decisionmakers
need to take a proactive approach to protect and promote worker health, supporting productivity and to reduce legal liabilities associated with occupational
disease.
Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines
for the treatment of cancer and other
diseases with high unmet patient
need, announced today that it has begun a Phase 1b...
The shipment contained more than 3 tons of urgently
needed medical aid
for patients with storm - related illnesses and injuries, as well as chronic
disease medicine to replace medications lost in the storm.
he also healed my husband from a deadly
diseases which i cant say we conducted a test and my husband came out positive after spending money in the hospital
for years.Thank you So much if you
need his help you can contact him via his private mail
[email protected] you will not regret it thanks
Since we all
need evolution
for the flu vaccine and sick individuals with
diseases such as AIDS
need it, it only makes sense that our politicians should step up and make a clear stance in favor of it.
While conservatives may balk at her religious identity
for any number of reasons — and have done so, no citation
needed — Christian leaders Perry Noble to megachurch pastor Zachery Tims have both publicly suffered from addiction (the latter eventually succumbing to the
disease).
some r powerless over their secksal urges
for secks with opposite secks, finding their
diseased cups
need 2 b emptied and refilled with god and by god in his way and in his time, he may open new vistas
for secksal fulfillment undreamed of b4.
There is a
need for thoughtful people to make some discriminations between and within religious groups — to look
for curing impulses that are latent in the faiths that so easily can spread
disease.
What is left, then, is a
need for thoughtful people to make some discriminations between and within religions groups, to look
for curing impulses that are latent in faiths that so easily can spread
disease.
After one particularly offensive show on Aug 19, 2010 where he and his cohost, Crank, spent the morning railing against the «mentally
diseased perverts» everyone else calls gay, preaching that women aren't equal to men and should be home raising the kids and making dinner, and Blacks
need to kick their drug habits and get a job instead of freeloading off his hard earned tax dollars by trading in their food stamps
for drug money, we started a blog documenting his abuses on the air waves.
And then I gave Adam syphillis, cholera, typhus, leprosy, rabies, malaria, and tuberculosis all simultaneously, because I'm a real ass... and I
needed a human vector
for some of these historic
diseases.
I kind of think it is the least we could do
for them seeing as how we stole their land, gave them blankets covered in
disease, hooked them on alcohol, massacred the buffalos, do I
need to go on?!? Oh, I forgot the whole slaughtering them
for their lands thing.
When this has gone on
for a while, the «pull» of increasing production in the form of new jobs, greater availability of materials to meet basic
needs and more money
for investment will lift the bottom line of poverty above destitution and eliminate the worst ravages of hunger,
disease and deprivation generally.
This focus on building Christian community will seem outrageous to some in view of the world's
needs, but it is a strength
for those who see the weakening of communal commitments and loyalties as modernity's fundamental
disease.
For evidence, one
need only note how the diet of those living in poor countries saves them from many of the
diseases that plague affluent Americans.
It must fruit in action to challenge and overcome the evils of society with its poverty, ignorance and
disease, its wars and destructive conflicts, its prejudice, oppression, chicanery and quest
for profit and power, its insensitivity to the deep
needs of persons.
When we think of all that has come from him in the impulse toward human freedom and dignity — the challenge of ignorance and the attempt to remedy it, the concern
for and conquest of
disease, the sensitivity to the
needs and plight of the weak, destitute, helpless, and those in every kind of suffering, the stabilizing of the inner lives of millions of his followers around the world, and the fostering of a prophetic attack on such giant social evils as prejudice, injustice, and war — when we consider the things that have stemmed from this «penniless teacher of Nazareth,» we are dull indeed if the wonder of it does not sweep over our souls.
And when we rid the world of poverty, ignorance and
disease and provide
for the
needs and pleasures of everyone, human venality will cease.
With all due respect to In»N Out, Chick - Fil - A and Tyson, I don't
need you to state your «morals» to know what you stand
for — poisoning our country through your disgusting fat foods which makes our citizens obese and leads to a significantly higher risk to many deadly
diseases.
He must be found in man's strength, not his weakness; in life's goodness, not in death and guilt alone.11 Bonhoeffer's question boils down to this: If by science man solves the problems of hunger and
disease, if by education the problems of guilt, if by psychiatry the ills of the mind, if man's other
needs can be met, what room is left
for God?
He or she just
needs to be the «attending physician,» defined in the new California statute as a doctor having «primary responsibility
for the health care of an individual and treatment of the individual's terminal
disease.»
Microfiltration and ultraviolet light technology purify the water so there is no
need for antibiotics or chemicals to combat
disease.
I was diagnosed with crohns
disease a year ago and its been really difficult
for me to find the right diet which suits my body and my illness»
needs.
The prevalence of celiac
disease and gluten sensitivity among millions of adults and children has created the
need for gluten - free recipes that are as nutritious and tasty as their traditional counterparts.
I love that she addresses different
needs, such as autoimmune
disease or athletic performance, so her book is useful
for every member of my family.
According to the Centers
for Disease Control and Prevention, you
need to consume 28 grams of fiber per day, based on a typical 2,000 - calorie diet.