• Alfred J, Uberti M, Dovlatyan M, Li Z, Smith D, Weiss J, Jubian V, Grenon M, Li G, Doller D and Brodbeck R: The Synthesis and invitro pharmacology of the selective mGLUR5
negative allosteric modulator (NAM).
The PI of the proposal has also experience in cheminformatics method development for chemical biology and therapeutic development (Mueller, R., et al.; «Discovery of 2 -(2 - Benzoxazoyl amino)-4-Aryl-5-Cyanopyrimidine as
Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu5): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound»; ChemMedChem; 2012; 7; 406).