Sentences with phrase «negative response to insulin»

Not exact matches

Ezio Bonifacio, Ph.D., of the DFG Center for Regenerative Therapies Dresden, Technische Universitat Dresden, Germany and colleagues randomly assigned autoantibody - negative, genetically at - risk children to receive oral insulin at varying doses (n = 15) or placebo (n = 10) once daily for 3 to 18 months to assess whether oral insulin can induce a potentially protective immune response without causing adverse effects.

A sustained modest weight - loss of five to 10 % body - weight is associated with improvements in various indices of cardiometabolic health including but not limited to insulin sensitivity, vascular function, blood pressure and lipid levels.3 These beneficial effects of weight - loss can be partially explained by accompanying reductions in adipose tissue mass and dysfunction.5 There is however, some evidence to suggest that energy restriction (ER) alone can confer metabolic changes which are independent to those of weight - loss, by facilitating an acute negative energy balance 6 - 9 and / or by activating adaptive stress response pathways.10