Sentences with phrase «negative symptom patients»

«We demonstrated that quality can be accomplished across the sites, but consider a different approach to the design,» she said, explaining that rather than treating negative symptom patients as one homogenous target, priority should be given to exploring the usefulness of novel mechanisms in separate negative symptom domains to better define the target population and maximize the chance of success before launching large phase III trials.

Not exact matches

These findings suggest that negative symptoms are associated with abnormalities in how patients weigh the cost of the effort needed to receive a reward or reach a goal.

Importantly, these abnormalities were seen consistently only in those patients with high levels of negative symptoms.

They found that schizophrenia patients, especially those with prominent negative symptoms, were more likely to choose the less demanding tasks that provided smaller rewards and were less likely than healthy subjects to choose more demanding tasks that offered greater rewards.

«After a negative stress test, we may be likely to tell a patient, «You're good, your symptoms today are not from your heart — there's no coronary blockage,» and patients walk away feeling like Superman,» Le said.

Two Florida health care workers who reportedly fell ill with flulike symptoms after coming in contact with a patient suffering from MERS have tested negative for the virus, according to health officials.

Narcissism is only considered a pathological phenomenon if the condition has a negative impact on the patient and if he or she develops symptoms of narcissistic personality disorder.

«While longitudinal studies are needed to confirm our results, this study suggests that boosting proline levels in patients with the Val / Val gene may help address negative symptoms, whereas increasing proline in patients with the Met / Met gene may have the opposite effect,» said Dr. Clelland.

The researchers also evaluated negative symptoms in 43 patients with bipolar disorder, about half of whom were treated with valproate.

In this study, the researchers compared the severity of negative symptoms and proline levels in 95 hospitalized schizophrenia patients with variants of the COMT gene.

The authors conclude that valproate may be effective for treating negative symptoms in psychiatric patients with two copies of the «Val» variant of the COMT gene, which breaks down dopamine in the brain.

Among those patients who were being treated with valproate (approximately one - third of the schizophrenia patients), negative symptoms were more severe in those with the Met / Met gene than in those with the Val / Val gene.

In the roughly 40 percent of patients with this genotype, higher levels of proline (a neuromodulator that is increased by valproate), correlated with fewer negative symptoms.

In patients who have a «Met» variant of COMT, rising levels of proline appeared to do the exact opposite: these patients had more or worse negative symptoms, and the symptoms did not improve with valproate.

In contrast, higher proline levels were associated with greater negative symptom severity in patients with the Met / Met gene.

A drug prescribed to many patients with schizophrenia or bipolar disorder may decrease negative symptoms for people with a certain variant of the COMT gene, suggests a new study from researchers at Columbia University Medical Center (CUMC).

The trials were carried out over 201 sites, with each trial including about 600 patients with persistent, predominant negative symptoms of schizophrenia.

While caregiver assistance can be beneficial to patients, such care may have negative consequences for caregivers, including poor health - related quality of life, emotional distress, caregiver burden, and symptoms of post-traumatic stress disorder.

Some physicians will recommend a throat culture even when the rapid test is negative, if the patient's symptoms seem to warrant it.

In patients with typical symptoms of histamine intolerance that are triggered by histamine - rich food and alcohol, with intolerance of drugs that liberate histamine or block DAO, and with a negative diagnosis of allergy or internal disorders, histamine intolerance should be considered.

They should be within normal range (as defined by the clinic the patient is using) in order to maintain optimal health without experiencing the negative symptoms of aging.

In patients in whom the abovementioned symptoms are triggered by the corresponding substances and who have a negative diagnosis of allergy or internal disorders, histamine intolerance should be considered as an underlying pathomechanism.

A study in 2001 suggests that L - lysine can reduce blood sugar levels in Type 2 diabetes patients and reduce negative symptoms.

One study focusing on treatment - resistant schizophrenic patients found that high - dose glycine in association with antipsychotic medication could significantly alleviate negative symptoms associated with this mental illness1.

Even integrative medicine doctor Andrew Weil recommends cancer patients avoid the tea because while doing nothing for cancer, it can have negative side effects causing nausea, vomiting, increased bowel movements, frequent urination, swollen glands, skin blemishes, flu - like symptoms, and slight headaches.

To be considered a candidate for Low T treatment, a patient must have both verifiable low testosterone levels and quantifiable negative symptoms.

«Every day, patients with Lyme disease are told their symptoms can not be caused by Lyme, because they test negative on antibody tests or because they have received a single course of antibiotics.

In any case, with careful management of any secondary problems such as gingivitis or chronic flu symptoms, most FIV positive cats can enjoy a good quality of life for almost as long as an FIV negative patient.

Abilify affects the brain's dopamine production to reduce negative symptoms of conditions such as depression and bipolar disorder, but it may create an overabundance of dopamine in some patients.

Based on a negligence investigation the patient will then go away, and feel reassured that they have had their definite investigation i.e., a colonoscopy which was negative; they will then treat the patient for a different condition, such as Irritable Bowel Syndrome (IBS), which causes similar symptoms as bowel cancer.

Intentionality and knowledge were equally important in predicting responsibility for positive symptom behaviours, while intent was the most important predictor of responsibility for negative symptom behaviours with the patient capacity playing a significant but minor role.

Therapy mostly seeks to educate patients about their disorder, and help them cope with the negative emotions that symptoms can cause.

There are well - documented associations between posttraumatic stress disorder (PTSD) and intimate relationship problems, including relationship distress and aggression, 1 and studies demonstrate that the presence of PTSD symptoms in one partner is associated with caregiver burden and psychological distress in the other partner.2 Although currently available individual psychotherapies for PTSD produce overall improvements in psychosocial functioning, these improvements are not specifically found in intimate relationship functioning.3 Moreover, it has been shown that even when patients receive state - of - the - art individual psychotherapy for the disorder, negative interpersonal relations predict worse treatment outcomes.4, 5

The relationship between depressive symptoms and step count has only been assessed in specific populations with small sample sizes, such as low - socioeconomic status Latino immigrants, 16 elderly Japanese people17 or patients with chronic conditions such as heart failure18 19 or chronic obstructive pulmonary disease.20 21 Studies yield contradictory results, with some observing no association between depressive symptoms and daily step count, 19 21 while others report a negative correlation.16 — 18 20 In one cross-sectional sample of healthy older adults, an inverse association between depressive symptoms (using the Goldberg Depression Scale - 15) and accelerometer measured daily step count disappeared after controlling for general health and disability.22 While a systematic review suggests reduced levels of objectively measured PA in patients with depression, 23 it is not known whether this association is present in those at high risk of CVD and taken into account important confounding such as gender and age.

Results indicate that for both patients and spouses, own mean self - rated health was associated with own depressive symptoms, and change in self - rated health had a significant negative association with change in own depressive symptoms.

Moreover, change in own self - rated health over time had a significant negative association with change in own level of depressive symptoms for both patients and spouses.

In the patient sample, attachment style did not mediate the relationship between ChM and negative symptoms, whereas attachment style was found to be a mediator in the sibling sample.

ChM predicted negative symptoms in patients and siblings.

There are inconsistent findings of associations between EE and overall levels of symptoms, with some studies finding positive correlations13, 14,38,41 and others finding no relationship.21, 24,28 In line with research with relatives, 3 there is, however, more consistent evidence of a positive association between EE and a poorer level of social functioning or negative symptoms.11, 14,21,23,24,29,42 The high level of disengagement of these patients may be a key factor in evoking criticism in staff.

Moore et al42 also found that low EE staff reporting motivating patients, eg, they were able to describe ways of helping patients to manage negative symptoms.

In Study 1, depressed patients voicing more explanations for negative events showed (nonsignificantly) higher correlations between attributional style and depressive symptoms.