Sentences with phrase «nematode model»

This discovery offers promising possibilities for functional studies of lipid metabolism in a nematode model system.

Not exact matches

One of his colleagues studies aging in nematodes (Caenorhabditis elegans), and he's considering changing his model organism.

In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic, cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model for aging studies in labs, activate genetic pathways completely separate from those found in long - lived egg, or oocyte, cells.

Esvelt plans to develop CRISPR gene drives in nematode worms — a fast - reproducing model organism — that are designed to spread a genetic modification in a local setting and then fizzle out, a concept that other scientists are pursuing.

He presented his idea one day to a roomful of about 30 colleagues at Yale's «Worm Meeting,» the weekly gathering for researchers studying C. elegans, the lowly nematode widely used as a model organism in developmental biology.

To test their theory, Xiaoli Guo, a post-doctoral researcher in Mitchum's lab and first author of the study, synthesized the CLE - B nematode peptide and applied it to the vascular cells of Arabidopsis, a model plant system used in plant research.

Together with scientists from Columbia (USA), Olomouc (Czech Republic), Warsaw (Poland), Osaka (Japan) and the Freie Universitaet Berlin, the researchers at the University of Bonn have used Arabidopsis thaliana as a model plant to discover that the beet cyst nematode itself produces the plant hormone cytokinin.

Finch's ideas about senescence from his grad school days have also held up: The popularity of the Hayflick model has declined as other research questioned its relevance to aging in whole organisms, and recent studies in long - lived nematodes have confirmed Finch's hunch that brain hormones control aging (see Johnson Review).

Using genetic models in a variety of organisms — yeast, nematodes, fruit flies, zebrafish — PLab aims to identify candidate treatment compounds for each disease, which can then be refined and taken to the clinic with partner companies.

In the new study, Lee and his colleagues studied piRNAs produced by cells in the reproductive system of the nematode worm, C. elegans, a classic model organism studied by scientists to understand basic biological processes.

The objective is to support innovative projects dedicated to the development and the study of rare disease models using small animals (mouse model excepted) such as zebrafish, drosophila, nematode, rat and rabbit.

We aim to address this question using molecular biology tools, microscopy and genetics in the model organism C. elegansand hope to extend our knowledge by studying other nematodes, namely Caenorhabditis briggsae and Pristionchus pacific us.

Non-mammalian animals like zebrafish, fruit flies, nematode worms and even seemingly more exotic creatures like salamanders and Mexican blind cavefish provide powerful experimental models for understanding fundamental biology and disease mechanisms.

Our strategy is based on the combination of genetics, imaging, electrophysiology and biochemistry in the nematode Caenorhabditis elegans (for more information on C. elegans see «an overview of the model organism C. elegans»).

To identify novel genes and conserved cellular processes that regulate the biology of K2P channels in vivo we take advantage of the powerful genetic tools available in the model nematode Caenorhabditis elegans.

Dr. Hansen's group focused on investigating the molecular mechanisms by which the nutrient sensor TOR modulates aging, using the nematode C. elegans as her primary model organism.

This year the organizers overtly recognized the history of our biomedical research niche in which C. elegans nematodes are used as a model organism (see our SAGE blog on how C. elegans models are used to study aging).

Our lab uses a variety of model systems, such as the nematode C. elegans, as well as in vitro culture systems, to address fundamental questions in cell cycle control during development and tissue formation.

In a screen of nearly 200,000 compounds, Tardiff and collaborators identified one chemical entity that not only reversed alpha - synuclein toxicity in yeast cells, but also partially rescued neurons in the model nematode C. elegans and in rat neurons.

Every year, VerMidi gathers the french research community using the model nematode C. elegans.

Role of extracellular polymeric substances in polymicrobial biofilm infections of Staphylococcus epidermidis and Candida albicans modelled in the nematode Caenorhabditis elegans.

They next turned to a couple of model organisms with more cells — nematodes, also known as C. elegans, and fruit flies, or Drosophila.

The animal model used for this study is a nematode worm genetically engineered to produce human alphasynuclein in its muscles.

The animal model used for this study, C. elegans, is a nematode worm genetically engineered to produce human α - synuclein in its muscles.

The researchers first discovered ascarosides as a signaling molecule in C. elegans, a nematode used as a model organism to study cell, developmental and nervous system biology, as well as human aging and diabetes.

In particular, I focus on chromosome segregation and cell division, using the nematode C. elegans as a model system.

Instead of focusing on marine animals, they use animal models such as freshwater zebrafish, salamanders, fruit flies and nematode worms that share many of their genes with humans.

As one of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the basic molecular biology of aging, from assisting in the investigation of how specific drugs can extend lifespan in simple model organisms such as the nematode C. elegans, to facilitating studies in various animal models of age - related disease.

Researchers removed the gene for GFP from jellyfish, cloned it, and introduced it into the cells of the bacterium E. coli and in C. elegans, a soil nematode widely used as a biological model.

The model nematode Caenorhabditis elegans is associated with a distinct microbial community under natural conditions.

Nippostrongylus brasiliensis, a nematode parasite of rodents, has a parasitic life cycle that is an extremely useful model for the study of human hookworm infection, particularly in regards to the induced immune response.

In selecting the highly adaptive metaphor of the nematode on which to base the cycle of work, de Vries brings to bear a ubiquitous, resilient notion of the artist and art itself, modeled on a worm so prolific and present in all aspects of life that, according to the scientist Nathan Cobb, if