A better understanding of aberrant brain receptor signaling that leads to
nerve cell dysfunction could reveal a target for therapy, according to the authors.
The latter substance, phosphorylated tau, is responsible for neurofibrillary tangles, which are suspected of contributing to
the nerve cell dysfunction in the brain that is responsible for Alzheimer's memory symptoms.
Not exact matches
In EAE, as with MS, immune
cells attack a
nerve cell protein called myelin, causing symptoms ranging from impaired vision to severe motor
dysfunction and even death.
Aguirre, J.A.; Kehr, J.; Yoshitake, T.; Liu, F.L.; Rivera, A.; Fernandez - Espinola, S.; Andbjer, B.; Leo, G.; Medhurst, A.D.; Agnati, L.F.; Fuxe, K. Protection but maintained
dysfunction of nigral dopaminergic
nerve cell bodies and striatal dopaminergic terminals in MPTP - lesioned mice after acute treatment with the mGluR5 antagonist MPEP.
On the surface, the disease appears relatively simple, with high pressure (intra-ocular pressure, or IOP) within the eye associated with the death of
cells in the retina and optic
nerve dysfunction.
Cognitive
dysfunction happens when
nerve cells start to die and there is malfunction in
nerve communication, similar to Alzheimer's in humans.
Senility is commonly called «cognitive
dysfunction» and is related to degenerating brain and
nerve cells in aging pets.