The previously unknown
nerve cell shape is now presented in the journal Neuron by a research team from Heidelberg, Mannheim and Bonn.
Not exact matches
While you are making adjustments for your changing
shape, there are a lot of changes going on inside your womb as your baby, who was just a cluster of
cells a couple of months ago, has organs,
nerves, muscles and is looking more like a little person.
A growing body of research indicates that the B2M - MHC I complex, which is present in all
cells in the body except red blood
cells and plasma
cells, can act in the brain in ways not obviously related to immunity — guiding brain development,
shaping nerve cell communication, and even affecting behavior.
BRAIN CANDY A new database offers a deep look at living human
nerve cells, revealing elaborate branching structures and myriad
shapes, such as in this neuron called a pyramidal
cell (
cell image, left and 3 - D computer reconstruction, right).
So far, researchers with the Allen Institute for Brain Science in Seattle have described the intricate
shapes and electrical properties of about 100
nerve cells, or neurons, taken from the brains of 36 patients as they underwent surgery for conditions such as brain tumors or epilepsy.
While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia
cells, the star -
shaped cells that play an important role in the physical structure of the brain as well as in the transmission of
nerve impulses.
The team looked for these
cells in nonliving brain samples in two ways: molecular markers that tag dividing
cells and young
nerve cells, and telltale
shapes of newborn
cells.
Consider that the
nerve cells of a human embryo have a cool quadrillion connections to make before a basic baby can take
shape.
The spiral -
shaped organ of Corti, found in the cochlea, houses the sensitive hair
cells that convert sound vibrations into
nerve impulses.
These two, almond -
shaped clumps of
nerve cells deep in the brain are sometimes referred to as the emotional thermostat for their role in the processing of emotions, particularly fear.
In addition, when the structure of the flies» ears was examined in detail, the researchers discovered that
nerve cells of the noise - rattled flies showed signs that they had been exposed to stress, including altered
shapes of the mitochondria, which are responsible for generating most of a
cell's energy supply.
Some of these
cells lost their star
shape and began to form new
nerve cells in a brain region responsible for smell.
This process, called
cell differentiation, gives rise to all the various
cell types, such as
nerve, muscle, or blood
cells, which are diverse in
shape and function and make up tissues and organs.
Scientists studying brain diseases may need to look beyond
nerve cells and start paying attention to the star -
shaped cells known as «astrocytes,» because they play specialized roles in the development and maintenance of
nerve circuits and may contribute to a wide range of disorders, according to a new study by UC San Francisco researchers.
The team studied the anesthetic ketamine, which blocks NMDA (N - methyl - D - aspartate) receptor proteins that enable charged particles like calcium to flow into
nerve cells, like electric switches that trigger and
shape messages.
Nerves and heart muscle start to struggle as vital communication channels in the
cell membranes are squeezed, and many proteins can not fold into their correct three - dimensional
shape properly, becoming physically deformed.
The nanoparticle's
shape gives it more surface area than spherical particles, improving the surface protein's ability to bind with receptors on
nerve cells that serve as a gateway to the nervous system.
Abstract T - type calcium channels are key contributors to neuronal physiology where they
shape electrical activity of
nerve cells and contribute to the release of neurotransmitters.
When prion proteins fold into a different
shape they produce indigestible tangles, which can kill or damage
nerve cells.
This visualization shows tightly - packed DNA in a mouse
cell's nucleus at different stages of development, seen here in a semi-triangular form as a mature
nerve cell; in a roundish
shape as a multipotent stem
cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized binding protein (HP1β knockout) affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.
The resulting
shapes recall densely packed alpine forests, upended root systems, or
nerve cells dyed for the microscope; nature seems to be mimicking itself.