33) Progressive Retinal Atrophy — this disease of the eye is when
the nerve cells at the back of the eyeball slowly degenerate (or fail), which can lead to blindness.
While HSV — 1 remains latent in nerve cells situated at the base of the neck, HSV — 2 remains dormant in
the nerve cells at the base of the spine.
Genital herpes resides in
the nerve cells at the base of the spinal column.
To do this, they used specially bred flies with genes that could be turned off in groups of
nerve cells at high temperature.
One type of stem cell can produce multiple types of
nerve cells at different stages of the brain's development.
We can look at many
nerve cells at the same time while simultaneously charting behavior.»
Using the standard timing protocol, the two enzymes do not reach peak activation inside
a nerve cell at the same time, a hint that the usual way of doing things might not be the best way.
Does it look like this medicine would actually protect or nourish
the nerve cell at the time or parallel to when the damage is accumulating?
Not exact matches
The companies» R&D will focus on on a gene mutation present in a wide swath of patients with ALS, a degenerative nervous system disease that eats away
at nerve cells and weakens muscles.
The difficulties associated with obtaining
nerve tissue
at the correct stage of development and differentiation from aborted embryos means that foetal tissue transplantation is no longer in favour, but the creation of human embryos specifically as sources of stem
cells, and the push to use «spare» embryos from IVF treatments is gatheringmomentum.
Thus,
at the lowest level, electrons tend to unite and converge in the atom; atoms converge by molecularization, crystallization; molecules unite by polymerization;
cells unite by conjugation, reproduction, association;
nerve ganglions concentrate and localize to form a brain by what might be called a process of cephalization; the higher animal groups form colonies, hives, herds, societies, etc.; man socializes and forms civilizations as foci of attraction and organization.
In a similar vein Mr. Percival Lowell writes: «When we have, as we say, an idea, what happens inside of us is probably something like this: the neural current of molecular change passes up the
nerves, and through the ganglia reaches
at last the cortical
cells....
So
at day 14, the number of
nerve and brain
cells in the human embryo is zero, and it has less complexity than the simplest microscopic worm and less feeling or intelligence than a parasite in dirty drinking water.
Incredible Brain Development
At birth a baby's brain contains 100 billion
nerve cells (or neurons), all she will ever have, but not the programming of those
cells.
Although these spots themselves are harmless, if some of the spots are bigger than a 50 cent coin, then it could be due to Neurofibromatosis (NF), which is a genetic disorder of the nervous system that causes abnormal
cell growth of
nerve tissues or benign tumours to form on the
nerves anywhere in the body
at any time.
Researchers are looking
at delays or abnormalities in brain development of
nerve cells that are responsible for heart and lung function.
Now, Nicole Kallweit and her colleagues
at Laser Zentrum Hannover in Germany have found evidence for the latter: their system did not work in guinea pigs which had intact auditory
nerves but were missing their hair
cells.
«The discovery of this special class of
cells that sit right
at the
nerve endings where HSV - 2 is released into skin is changing how we think about HSV - 2 and possible vaccines,» said Corey.
The best explanation so far, says Henrietta van Praag, a neurobiologist
at the National Institute on Aging, is that exercising the heart somehow stimulates growth factors to produce new
nerve cells in the brain.
The main cog in the human biological clock is the suprachiasmatic nucleus (SCN), a group of
nerve cells in a region
at the base of the brain called the hypothalamus.
At the same time, the activity of hundreds of
nerve cells was measured with so - called microelectrode arrays.
Results from the new study suggest immunostimulant molecules that target neutrophils
at nerve injury sites might enhance clean - up and promote
nerve cell repair.
BRAIN CANDY A new database offers a deep look
at living human
nerve cells, revealing elaborate branching structures and myriad shapes, such as in this neuron called a pyramidal
cell (
cell image, left and 3 - D computer reconstruction, right).
Samuel Weiss, director of the Hotchkiss Brain Institute
at the University of Calgary, and his colleagues reported that
nerve cells sprouted in the olfactory bulb, the seat of the sense of smell, and in the hippocampus, the brain's memory bank.
In fact, the peptide prevented VCP from relocating to mitochondria
at all, and prevented
nerve cell death.
Scores of laboratories
at universities and in private industry are uncovering how to use these
cells, which transform into neurons, astrocytes (the
cells that regulate transmission of electrical impulses in the brain) and oligodendrocytes (which insulate
nerve fibers with a fatty coating).
With neural prosthetic technology — microchips that can «listen» to many neurons
at the same time — researchers are able to find correlations between the activity of many
nerve cells.
But there are also certain things that if an investigator like [s] to do, and I came from cellular neurobiology having learnt from Grundfest and from Wade Marshall and from my period
at the NIH how to study
nerve cells in the brain; and I was until that point studying complex organisms — a cat; Aplysia fitted me to a tee.
But their prominence
at sites where
nerve cells are damaged by the disease means they deserve careful scrutiny in the desperate search for ways to arrest the most salient cause of dementia.
He showed that short - term memory involves increased levels of neurotransmitters
at the synapses, the communication sites between
nerve cells and long - term memory requires changes in the levels of proteins in the synapse.
In the current study, Frank Longo, MD, PhD, and others
at Stanford University, tested LM22A - 4, a drug that specifically binds to and activates the BDNF receptor TrkB on
nerve cells, in mice that model the disorder.
A newly characterized group of pharmacological compounds block both the inflammation and
nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted
at the Icahn School of Medicine
at Mount Sinai and published online this week in the journal Nature Neuroscience.
In research that has implications for diabetes and other metabolic diseases, an international study based
at UT Southwestern Medical Center found that the protein connexin 43 (Cx43) forms
cell - to -
cell communication channels on the surface of emerging beige fat
cells that amplify the signals from those few
nerve fibers.
«The compounds identified in this study, when administered orally, both reduced the inflammation that is a hallmark of multiple sclerosis and protected against the
nerve cell damage seen in mouse models of the disease,» said Jeffery Haines, PhD, a post-doctoral fellow
at Mount Sinai and the study's lead author.
When Laura Dugan, a neurologist
at Washington University in St. Louis, heard that buckyballs absorb free radicals, she designed experiments to test whether or not buckyballs could slow down
nerve cell death.
The electrodes detected waves of synchronized
nerve impulses sweeping through the retinal tissue, in patches of up to 100
cells at a time.
In contrast, the new method used on mice causes certain
nerve cells to fire
at a specific rhythm, generating brain waves that researchers believe may clear A-beta.
The study — which looked
at the action of Substance P within
nerve cells in the lab and in animal models — focused on acute pain, but Professor Gamper aims to look
at its role within chronic pain as well.
A team
at Emory University is embedding electrodes in glass cones filled with
nerve - growth factors that encourage brain
cells to sprout more dendrites and axons.
Researchers
at Georgetown University Medical Center recently discovered that these drugs also interact with specific proteins on the surfaces of
nerve cells — which could also lead to increased pain when patients wake up.
Cajal also figured out that
nerve cells are polar, meaning that signals enter the
cell through the shrubbery of the dendrites
at one end and leave through the other end
at the whiplike axon.
Researchers
at the University of Utah have unraveled how two proteinsUNC - 13 and syntaxinwork together to enable
nerve cells to communicate.
But
at some point, tau goes astray, too, and the
nerves lose their structural support, causing the
cells to collapse and die.
At the same time, the techniques of genetics and molecular biology began to reveal the intricate biochemical signals that synapses — the portals of
nerve cells — deploy during communication.
The brain harbors about 86 billion neurons, or
nerve cells, that have to be born
at the right time, migrate to the right place, and wire up in the right way if we are to survive and thrive.
BREAKING DOWN MULTIPLE SCLEROSIS Taking narrow aim
at the immune system isn't enough, so researchers are looking for new treatment targets within
nerve cells and even in the gut.
But most of those signals aren't coming from the
nerve cells, researchers reported November 15
at the Society for Neuroscience meeting.
At this point, there is no effective treatment for TON and the mechanisms of the optic
nerve cell death have been largely unclear.
«Our work could lead not only to a better understanding of the biology of the optic
nerve, but also to a
cell - based human model that could be used to discover drugs that stop or treat blinding conditions,» says study leader Donald Zack, M.D., Ph.D., the Guerrieri Family Professor of Ophthalmology
at the Johns Hopkins University School of Medicine.
In the current study, Yu - Shang Lee, PhD, of the Cleveland Clinic, together with Jerry Silver, PhD, of Case Western Reserve Medical School, and others, used a chemical that promotes
cell growth along with a scar - busting enzyme to create a more hospitable environment for the
nerve graft
at the injury site.