Sentences with phrase «nerve cells designed»

When we experimentally increased the expression of the microRNAs in model nerve cells designed to replicate the conditions of HD, the cells lived longer, indicating that these miRNAs may promote cell survival,» explained lead author Richard Myers, PhD, professor of neurology at BUSM.

Not exact matches

In an unexpected twist, two antibodies designed to fight Alzheimer's disease instead made nerve cells in mice misbehave more.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

When Laura Dugan, a neurologist at Washington University in St. Louis, heard that buckyballs absorb free radicals, she designed experiments to test whether or not buckyballs could slow down nerve cell death.

Using fluorescent antibodies designed specifically to light up the receptor in mice, the investigators observed it on vagus nerves, which serve as a main biochemical connection between airway cells and the brain.

When scientists gave mice an oral drug called LM11A - 31 (designed to prevent neural degeneration in Alzheimer's patients) just hours after a complete spinal cord injury, it limited the death of cells that protect nerve fibers, allowing test rodents to retain their ability to walk and swim.

Implantable prostheses designed to deliver electrical stimuli directly to the auditory nerve hold considerable promise for people with a type of deafness in which the sensory hair cells of the inner ear are damaged

Alterations in the genetic coding for a nerve cell receptor, which detects a chemical signal that is key to behavioral change, could point the way to designing therapies most effective for patients suffering from schizophrenia, drug addiction and other mental illnesses.

Implantable spinal cord stimulators and peripheral nerve stimulators designed to interrupt nerve pain impulses were developed more than 30 years ago, but the devices work by interacting with sensory nerve cells, leading to numbness, tingling and other side effects.

Together, the knowledge gained in this project will generate new insight into the pathology of the disease as well as help design future therapies for preventing progressive loss of retinal nerve cells and degradation of vision in glaucoma.

A team of researchers from the University of Chicago, Northwestern University, the University of Illinois at Chicago and the U.S. Department of Energy's (DOE's) Argonne National Laboratory have engineered silicon particles one - fiftieth the width of a human hair, which could lead to «biointerface» systems designed to make nerve cells fire and heart cells beat.

A series of six cell culture assays was designed to mimic multiple old - age - associated pathways of central nervous system (CNS) nerve cell damage, and drug candidates were required to show efficacy in all of these assays before being moved forward into animals.

Summary: Researchers have identified a region on the surface of nerve cells that may be essential for the actions of anesthetics, opening a door to rational design of new medications.

After 155 years of searching, researchers have identified a small region on the surface of nerve cells that may be essential for the actions of inhaled anesthetics, opening a door to rational design of new pain medications.

«ISIS - SMNRx is specifically designed to intervene in the nerve cell's RNA machinery by improving splicing efficiency.