Sentences with phrase «networks of genes»

The data generated and the methods and tools developed within the project will also lead to a better understanding of the complex networks of genes and gene regulatory systems behind colorectal cancer.

Krogan believes that mutations in a few key networks of genes cause diseases like cancer, even though the individual genes that are mutated in tumors vary between different people and different types of cancer.

Zimmer: I was really blown away when I spent the time to understand some of the networks of genes that E. coli uses to deal with things like overheating or something, where you have got 10 or 20 genes that are fit together, kind of like the components in [a] the circuit.

The resulting papers published in Nature all tell similar stories of shared evolution between species — for instance, the commonalities of regulatory networks of genes and the transcription factors that control their activation.

Underlying the most common human diseases, however, are entire networks of genes.

Using a computational technique called network diffusion, the team identified networks of genes that are interrelated through their connection to the ASD genes in the databases.

This gene then «switches on» networks of genes that form the male or the female phenotype.

The researchers also identified networks of genes that were activated by the cholesterol lowering procedure and caused the regression of the atherosclerotic plaques.

«I wanted to do modeling of molecular biology and find out how we should put these networks of genes together conceptually to understand living systems.

Identifying groups of genes that work together, and then targeting these networks of genes, may lead to more effective treatments.

«But the discovery of this network of genes linked to epilepsy opens avenues for finding new treatments.

Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease - related genes.

Finally, the team identified a network of genes in these regions that exhibit changes in expression when the normal boost from serotonin is lacking, and these changes depended on how long the drug was given.

Doyle is now tackling a far bigger network of genes in E. coli: the master network responsible for governing its metabolism.

In the current study, the researchers report that NOTCH1 acts like a sensor on the endothelial cells — the cells that line the valve and vessels — detecting blood flow outside of the cell and transmitting information to a network of genes inside the cell.

But according to the evidence we uncovered, they may have retained the ancient network of genes to build them.»

Scientists of the Transfaculty Research Platform «Molecular and Cognitive Neurosciences» (MCN) at the University of Basel and the Psychiatric University Clinics have now described a network of genes that controls fundamental properties of neurons and is related to working memory, brain activity and schizophrenia.

Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.

The research team found that this non-coding RNA fragment maintains healthy cells through two mechanisms: Firstly by regulating the levels of DIRAS3, one of its neigboring genes that is involved in cell replication; secondly by suppressing a network of genes that prepare cells to change their shape and prepare for metastasis.

This process is called metastasis and requires a whole network of genes to regulate the transformation of cell shape and mobilization.

At the cellular level, the clock is controlled by a complex network of genes and proteins that switch each other on and off based on cues from their environment.

Suddenly, one minor nucleotide difference would be amplified across a network of gene differences.

The researchers then conducted a number of genetic analyses to piece together the network of genes responsible for this nutrient addiction.

A regulatory factor called Dorsal controls a network of genes crucial for development of fruit fly embryos.

Companion studies also shed light on the question of why boys are more likely to develop autism than girls, and begin to outline a network of genes whose activity is altered in the brains of individuals with autism.

'' Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses» will be published June 9 in Neuron.

In the associated paper, Vitkup, Iossifov and others use a novel form of analysis called NETBAG (network - based analysis of genetic associations) to identify «the large biological network of genes affected by rare de novo CNVs in autism.»

Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead...

«Investigating their genetic mutation revealed a whole network of genes that went awry, first causing septal defects and then the heart muscle dysfunction.»

Because of the single mutation in GATA4, virtually the entire network of genes regulated by GATA4 and TBX5 were disrupted, resulting in disease.

We also identified a «meditation effect» within the regular meditator group, characterized by a distinct network of genes with cellular functions that may be relevant to healthy aging, and this network was associated with increased expression of a number of telomere maintenance pathway genes and an increase in measured telomerase enzymatic activity.

Her team combed extensively through the literature and identified «the placebome,» a network of genes that influence the placebo response.

Not exact matches

«Twitter is one of the most widely used social media networks worldwide and despite the speed of technological innovation in the 21st Century, no other full - service bitcoin wallet offered this feature until now,» said Gene Kavner, founder and CEO of iPayYou as well as a former Amazon executive, as quoted by Pymnts.com.

Marshall points out that the relatively fast appearance of new animal species in this period is not driven by new genes, but rather by evolving from existing genes through «rewiring» of the gene regulatory networks (GRNs).

The genes, network of veins, nerves, and reproductive system, the way our most minuet details all work together.

Often, the genes of the new are present in the body of the old — they are the ideas, the social movements, the fair food networks that start life on the innovative edge, the social fringe, and move towards the middle where they give expression to the new systems that grows out of the old.

Ongoing projects include studies of gene - environment interactions and adverse pregnancy outcomes, as well as informed medical decision making demonstration projects in Medicaid maternity populations and within HealthWise, the nation's largest source of health information materials distributed through healthcare networks.

These people interbred at the edges of their separate populations, keeping the entire complex network interconnected — and so giving the ancient Kostenki man genes from three different groups.

Examples of gene networks in the hippocampus affected by brain trauma.

What unites the sociologists, physicists, biologists, and other scientists studying networks is the recognition that «whether they're networks of people, computers, genes, [or] neurons, they often obey similar mathematical rules and have similar properties,» says Nicholas Christakis, a professor of sociology and of medical sociology at Harvard Medical School in Boston.

EPFL scientists have now taken the first extensive look at a family of ~ 350 human proteins, showing that they establish a complex interplay with transposable elements to create largely human - specific gene regulatory networks.

Carlo Croce, a cancer researcher at Ohio State University in Columbus, and his colleagues created a diagram of interacting miRNAs for normal body cells by connecting them according to which genes they target and the function of those genes, in a way similar to analyses of human social networks.

Biologists could use an infusion of mathematics as well, says Iya Khalil, vice president of R&D at Gene Network Sciences Inc. in Ithaca, New York.

«Or we could use it to study the gene networks in diseases and get a better understanding of how those diseases work.»

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

«This study shows that NF - kB might coordinate a network of immune - suppressor genes whose products enable tumor cells to evade adaptive immunity,» he adds.

Several of the network genes Volkan and her team identified have counterparts in humans and other vertebrates, which suggests the same basic mechanism could be at work in building the nervous system in other animals too.

To learn which genes in the mussel make the byssal threads, the researchers first treated the threads with the enzyme pepsin to liquefy their interlocking networks of proteins.

By tweaking different fly genes and counting how many neuron types were produced as the flies matured, the team identified a network of five genes that work together like coordinated control switches to guide the precursor cells» transformation to mature neurons.

Korenberg was the early pioneer of studying these individuals with partial gene deletions as a way of gathering clues to the specific function of those genes and gene networks.