Sentences with phrase «neural cell level»

The Raman images now show protein activity at neural cell level, but the sensitivity is high enough for detecting areas that are even smaller — as is the case with the brain sample of the healthy person.

Not exact matches

Levels of NAD dropped, and the neural stem cells stopped dividing; they stopped renewing themselves; and they stopped being able to create important cells that insulate axons, the «wires» that carry electrical signals throughout the brain.

«We discovered that WS neural progenitor cells failed to proliferate due to high levels of cell death,» said Muotri.

Finally, the group examined human neural stem cells extracted from people with schizophrenia and found that these, too, showed higher levels of L1.

In mice and humans alike, the cerebral cortex — the outermost layer of brain tissue associated with high - level functions such as memory and decision - making — starts out as a spherical sheet of tissue made up of only neural stem cells.

Low levels of BMPs allow dorsal cell fate specification (e.g., neural tissue; formation of head structures), whereas higher levels of BMPs direct ventral cell fate specification (e.g., epidermis, blood, formation of tail structures).

These «delayed response tasks» suggest that working memory, at the level of brain cells, is the result of self - sustaining patterns of neural activity — a group of neurons starts firing when the initial information is presented and maintains that firing internally when the stimulus is no longer present until the animal acts on that information.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

The collaborative work conducted by the Terskikh and Muotri labs showed the drug decreased viral levels, reduced neural cell death and limited the amount of virus transmitted to babies.

Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels.

Day 7 and 42 mice had similar levels of DARPP32 - positive cells than the sham suggesting that the iPSCs had a time independent ability to differentiate into these mature neural cells.

Leukemia inhibitory factor (LIF): Altered LIF levels have been used to spur neural cells into greater activity that can better restore lost myelin sheathing on nerves.

The finding is based on studies of mice with altered levels of the growth factor PDGF in neural stem cells, which play a key role in the development of the eye.

Towards this goal, we build abstract mathematical as well as detailed biophysical models of neural cells and circuits across multiple brain regions (hippocampus, amygdala, PFC) and abstraction levels (single neurons, microcircuits, neuronal networks).

The signals can be localized in the brain and translated into digital images that portray neural activity level as a ratio of oxygenated to de-oxygenated hemoglobin, the iron - containing pigment in red blood cells.

10/10/2007 Researchers Reveal Repressor Protein Blocks Neural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... MNeural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... Mneural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... More...

Dr. Jennifer Garrison is interested in understanding how neuropeptides control behavior at both the cell biological and neural circuit level.

They went on to show that Sox10, a factor needed for the formation of skin pigment cells from neural crest stem cells during development, was present at high levels in naevi and melanoma samples obtained from both the mouse model and human patients.