Sentences with phrase «neural circuit mechanisms»

Our study forms the foundation to analyze the neural circuit mechanisms underlying preparatory activity in a genetically tractable model organism.Short - term memories link events separated in time.

Not exact matches

Researchers at Weill Cornell Medical College have uncovered a mechanism that guides the exquisite wiring of neural circuits in a developing brain — gaining unprecedented insight into the faulty circuits that may lead to brain disorders ranging from autism to mental retardation.

A better understanding of these mechanisms might make it possible to focus therapeutic interventions on specific neural circuits to improve treatment of neurological disorders in the future.»

In a study on mice, researchers at Karolinska Institutet have now been able to identify neural circuits and mechanisms behind this loss of sensory perception.

A team of researchers at the IRCM led by Frédéric Charron, PhD, in collaboration with bioengineers at McGill University, uncovered a new kind of synergy in the development of the nervous system, which explains an important mechanism required for neural circuits to form properly.

Understanding the dynamic mechanisms that lead to the emergence of brain functions through the development and continuous remodelling of neural circuits, and the constraints that disease and aging impose to this multi-modal plasticity has important implications that go beyond fundamental neuroscience, from education policies to brain repair.

Three basic mechanisms have been proposed over the years to explain the formation of specific neural circuitry: (1) an elaborate predetermined program encoded genetically in each neuron that unfolds according to rigid and unmodifiable rules, (2) a random process of trial and error in which growing nerve fibers that make the right connections are consolidated and those that fail are reabsorbed and (3) a general program of circuit formation that is brought to completion by an interplay between genetic and extrinsic factors.

At Weizmann, Dr. Spiegel will be establishing his own independent research group which will attempt to identify the molecular and cellular mechanisms through which experience alters the structure and function of neural circuits in the brain in behaviorally relevant ways and to understand how these processes, when they go awry, might give rise to psychiatric disorders.

Jin's lab employs a vast array of tools, including quantitative behavior, genetics and optogenetics, in vivo physiological and optical techniques to dissect the neural circuits and molecular mechanisms underlying action learning and selection in freely behaving mice.

These efforts also address neural function and memory, such as mechanisms employed by the brain to balance excitatory and inhibitory activity in neural circuits.

Major themes of Dr. Drevets studies have involved: 1) characterizing the pathophysiology of mood disorders using multimodal neuroimaging technologies; 2) delineating neural circuits in which dysfunction is associated with major depressive episodes; 3) elucidating effects of genetic variants associated with the risk for mood disorders on neural function, structure and receptor pharmacology; 4) investigating the neural mechanisms of antidepressant and mood stabilizing treatments, and 5) developing novel therapeutics for mood disorders.

He uses a variety of tools to uncover the neural circuits and molecular mechanisms underlying action learning and selection.

Part of Salk's Molecular Neurobiology Laboratory, Jin uses a variety of tools to uncover the neural circuits and molecular mechanisms underlying action learning and selection.

We are also characterizing the neural circuits through which vasotocin, the ancestral homologue of vasopressin, promotes context - dependent social withdrawal in male goldfish, as well as the receptor mechanisms that underlie its ability to have different behavioral effects in different social contexts.

However, little is known about the mechanisms by which hypothalamic neural circuits controlling behavior and metabolism sense protein availability.