They suspected that MSI1 — an RNA
binding protein — might be important in this process because it is involved in regulating the pool of
neural stem cells that are required for normal brain
development.
Amphimedon possesses homologues of bilaterian proteins involved in nervous system
development (for example, elav - and musashi - like RNA -
binding proteins,
neural transcription factors), pre - and post-synaptic organization (for example, Discs large) 42, endogenous and exogenous signalling (for example, G - protein - coupled receptors (GPCRs)-RRB-, and neuroendocrine secretion, although bilaterian peptide hormones are not detected (Supplementary Note 8.9).