Sentences with phrase «neural stem cell culture»

Cortical development and cortical stem cells The laboratory uses neural stem cell culture, transgenic model systems and retroviral vectors to study signalling pathways that are central in mouse cortical development and in particular in cortical stem cells.

Confocal microscopy of human neural stem cell culture infected with Zika virus (red).

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Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).

The students used a 3 - D printer to design a smaller and more cost - efficient bioreactor — a miniaturized culture device where neural stems cells are grown and eventually become small laboratory brains for research.

2 - D cell - culture and mouse experiments also provided key evidence of the virus's modus operandi; although the rodent brain doesn't harbor the full contingent of human neural stem cells, it has blood vessels and immune - system components that organoids lack.

«The culture conditions needed to grow various kinds of stem cells can be very tricky,» down to the source of the water, says neural stem cell biologist David Anderson of the California Institute of Technology in Pasadena.

To boost their odds, the researchers bathed the cells in culture media that encourage growth of neural stem cells.

Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.

In culture, neural stem cells (NSCs) can readily differentiate into neuronal and glial subtypes, but their ability to differentiate into region - specific neuronal cell types is limited.

In this study, we analyzed three different cultures of neural cells carrying trisomy of chromosome 21, which were generated by directed differentiation from induced pluripotent stem cells (iPS cells).

Ultimately, we use all this information to establish innovative culture techniques for generating unlimited neural stem cell sources for the derivation of specific types of clinically relevant neuronal or glial cells, for their use in disease modelling and drug discovery platforms, and towards refining their efficacy for future cell replacement - based therapy.

Two exogenous murine neural stem cells (NSCs) filled with the gap junction - permeable dye Calcein (green) and the gap junction - impermeable dye DiI (red) following engraftment to an organotypic stritatal tissue culture.

Now offering N21 - MAX and N - 2 serum free media supplements that will give you high - quality and consistent neural and stem cell cultures.

These results support data suggesting that excess HS oligosaccharides impair function of cellular adhesion molecules and disrupt normal polarization and orientation of cultured MPSIIIB mouse astrocytes or neural stem cells [52].