Not exact matches
But the next big question was whether these
cells could home
in on tumors
in lab dishes, and
in animals, like
neural stem cells.
Now head of her own
lab at Stanford, Heilshorn engineers proteins to aid
neural stem cells in healing injured brains and spines.
One of the team's most exciting new observations suggests a link between autism and a type of
neural stem cell called outer - radial glia (oRGs), discovered by the Kriegstein
lab in 2010.
The approach enabled a wide range of studies of human brain development, including implicating a new class of
neural stem cell recently discovered by the
lab in the evolutionary expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly
in infants infected
in utero.
Several years ago, one of the students
in Verma's
lab noticed that BRCA1 is very active
in the neuroectoderm, a sliver of embryonic tissue containing
neural stem cells that divide and differentiate into the brain's vast assortment of
cell types and structures.
They tested 120
neural stem cell lines
in the
lab for stability and robustness and
in animals for the capacity to engraft with minimal immune rejection.
Scientists
in the
lab have successfully generated
neural stem cells (NCS) from human embryonic
stem cells and human induced pluripotent
stem cells (these are
stem cells that have been reprogrammed from adult
cells).
In 2010, Kriegstein's lab discovered a new type of neural stem cell in the human brain, which they dubbed outer radial glia (oRGs) because these cells reside farther away from the nurturing ventricles, in an outer layer of the subventricular zone (oSVZ
In 2010, Kriegstein's
lab discovered a new type of
neural stem cell in the human brain, which they dubbed outer radial glia (oRGs) because these cells reside farther away from the nurturing ventricles, in an outer layer of the subventricular zone (oSVZ
in the human brain, which they dubbed outer radial glia (oRGs) because these
cells reside farther away from the nurturing ventricles,
in an outer layer of the subventricular zone (oSVZ
in an outer layer of the subventricular zone (oSVZ).
In the
lab for Human Brain and
Neural Stem Cell Studies we aim at developing experimental paradigms to systematically identify novel types of neural stem and progenitor cells that serve as building blocks for brain develo
Neural Stem Cell Studies we aim at developing experimental paradigms to systematically identify novel types of neural stem and progenitor cells that serve as building blocks for brain developm
Stem Cell Studies we aim at developing experimental paradigms to systematically identify novel types of
neural stem and progenitor cells that serve as building blocks for brain develo
neural stem and progenitor cells that serve as building blocks for brain developm
stem and progenitor
cells that serve as building blocks for brain development.
Multipotent
stem cells with
neural crest - like properties have been identified by our
lab and others
in the dermis of human skin.
Kirsten Obernier, PhD, a postdoctoral researcher
in Alvarez - Buylla's
lab, spent six years trying to understand how the brain avoids running out of
neural stem cells by catching the
cells in the act of dividing.
There he worked
in the Kaplan
lab, originally with the
Neural Group working to create a scaffold for a model of a three - dimensional interconnected neuronal network grown from human induced pluripotent
stem cells.
Neural stem cells are found
in adult or fetal brain and spinal cord or derived from embryonic
stem cells, which have the capacity to become any
cell type
in the body, or induced pluripotent
stem (iPS)
cells, tissue - specific
cells that are reprogrammed
in the
lab to behave like embryonic
stem cells.