Sentences with phrase «neurodegenerative brain disorder»
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Palm Oil - Derived Natural Vitamin E a-Tocotrienol in Brain Health and Disease: Scientific literature evaluating the therapeutic potential of tocotrienols (type of vitamin E found in abundance in palm fruit oil) for neurodegenerative disorders of the central nervous system, cancer treatment, and hypercholesterolemia.
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They also found that some of the athletes, none of whom suffered diagnosed concussions, didn't do as well as predicted on tests of learning and memory at the end of the season, although the study did not find «large - scale, systemic differences» in the brain scan measures, which the authors found «somewhat reassuring» and consistent with the fact that millions of athletes play contact sports for many years without developing progressive neurodegenerative disorders.
Specific plans for the research will remain to be developed, but potential areas under discussion include accelerating the pace of discovery to support the most innovative and promising science of the brain, including: chronic traumatic encephalopathy (CTE); concussion management and treatment; and the understanding of the potential relationship between traumatic brain injury and late - life neurodegenerative disorders, especially Alzheimer's disease.
The study also linked traumatic brain injury with the onset of neurodegenerative disorders, including mild cognitive impairment as well as Alzheimer's and Parkinson's diseases.
The discovery, which shows that the brain has a far greater ability to adapt and respond to changes than previously believed, could have significant implications on epilepsy, movement disorders, and psychiatric and neurodegenerative disease.
The discovery of a new mechanism that controls the way nerve cells in the brain communicate with each other to regulate our learning and long - term memory could have major benefits to understanding how the brain works and what goes wrong in neurodegenerative disorders such as epilepsy and dementia.
The projects vary slightly in their aims — the US BRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorBRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorBRAIN initiative will start by cataloguing the types of cells in the brain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorbrain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorbrain and how they wire together, while the China Brain Science Project is focused on developmental, psychiatric and neurodegenerative disorBrain Science Project is focused on developmental, psychiatric and neurodegenerative disorBrain Science Project is focused on developmental, psychiatric and neurodegenerative disorders.
By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder.
Neurodegenerative disorders devastate the brain, but doctors hope one day to replace lost cells
The ever - growing crowd of misfolded proteins form the aggregates seen in the brains of patients with neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.
PD is the second most common neurodegenerative disorder, primarily caused by the death of dopamine - containing neurons in the substantia nigra, a region of the brain involved in motor control.
Preclinical studies suggest that Cdk5 is a gene that is important for the normal wiring of the brain during early development and may be involved in some neurodegenerative disorders, including ALS, Parkinson's and Alzheimer's disease.
«Scientists search for the clocks behind aging brain disorders: Study of flies suggests neurodegenerative disorders may speed up aging process.»
But when the enzymes are over-activated, the brain produces an excessive level of neurotoxic byproducts, causing neuronal dysfunctions that lead to psychiatric disorders and neurodegenerative diseases.
Penn State researchers were the first to discover increased iron levels in the brains of some patients with the late - onset neurodegenerative disorders Parkinson's disease and Alzheimer's disease.
The technique has the potential to benefit a large population of patients with neurodegenerative disorders, where there remains a specific unmet need for blood - brain penetrating therapeutic delivery strategies.
Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.
«We're trying to get at the heart of the mechanism behind neurodegenerative diseases and with this research believe we've found one that seems to be commonly disrupted in many of them, suggesting that similar drugs may work for some or all of these disorders,» says Jeffrey Rothstein, M.D., Ph.D., a professor of neurology and neuroscience, and director of the Brain Science Institute and the Robert Packard Center for ALS Research at the Johns Hopkins University School of Medicine.
«Although we are currently looking at neurodegenerative disease, there is potential for the technology to be expanded to psychiatric diseases, chronic pain, seizure disorders and many other conditions affecting the brain and nervous system down the road.»
According to the National Alliance on Mental Illness: «It is too early to classify schizophrenia as either a neurodevelopmental (impairment of the growth and development of the brain) or a neurodegenerative (progressive loss of structure or function of neurons) disorder, as both seem to occur over the course of the illness.
In this neurodegenerative disorder, the frontal lobes of the brain are slowly eaten away, causing social and mood changes as well as cognitive decline.
Study finds a window of adaptability in newly formed brain cells; may lead to stem cell therapies for neurodegenerative disorders
A digital map of the aging brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests.
Because stem cells have the ability to develop into many different cell types in the body, researchers at USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery & Brain Repair have focused on using stem cells to restore function lost through neurodegenerative disorders or injuries.
The hallmark lesions of this neurodegenerative disorder arise from the accumulation of two proteins in the brain.
Established in 1979, the Sanders - Brown Center on Aging at the University of Kentucky is nationally recognized for its research, education and outreach, and clinical programs on healthy brain aging and neurodegenerative disorders.
Thankfully, it has good plumbing: Scientists have just discovered a cleansing river inside the brain, a fluid stream that might be enlisted to flush away the buildup of proteins associated with Alzheimer's, Huntington's and other neurodegenerative disorders.
These processes often break down as a result of aging, neurodegenerative disorders (e.g. Alzheimer's disease), or traumatic brain injury, and the new findings provide a roadmap to examine strategies to improve these functions.
«In the future, these may lead to treatments for a variety of brain disorders, including psychiatric and cognitive conditions as well as neurodegenerative diseases.»
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a debilitating neurodegenerative disorder that leads to paralysis and death due to the loss of motor neurons in the brain and spinal cord.
The institute is expected to focus on nervous systems and brain problems, specifically neurodegenerative diseases, sleep disorders, mechanisms of brain repair, and behavioral disorders.
From the bakery to the brain business: developing inducible yeast models of human neurodegenerative disorders.
Such implants can be difficult to insert, however, and can be incompatible with many kinds of experiments, such as studies of development, during which the brain changes size, or of neurodegenerative disorders, during which the implant can interact with brain physiology.
The brains of aging humans are prone to neurodegenerative disorders and we are unable to counteract neuronal loss by regenerating lost cells.
SAN FRANCISCO, CA — April 29, 2012 — Scientists at the Gladstone Institutes have determined how specific circuitry in the brain controls not only body movement but also motivation and learning, providing new insight into neurodegenerative disorders such as Parkinson's disease — and psychiatric disorders such as addiction and depression.
«Huntington's — an inherited and fatal disorder that leads to problems with muscle coordination, cognition and personality — is characterized by the toxic buildup of a mutant form of the huntingtin protein in the brain,» explained Dr. Finkbeiner, who directs the Taube - Koret Center for Neurodegenerative Disease Research at Gladstone.
«We were therefore surprised to find that it also plays important roles in neurons, which don't divide, and in a neurodegenerative disorder that is characterized by a loss of these brain cells.»
Parkinson's disease is a neurodegenerative disorder of unknown cause that particularly affects areas of the brain which are involved in movement control.
For many neurological, neurodegenerative and psychological disorders, the extent to which they are manifest as a consequence of uniquely human brain specializations or have a shared origin with other primates remains a central topic in neuroscience.
Core areas of research at the institute include work on brain - computer interfaces to aid patients with spinal injury and paralysis; innovative advances in computational neuroscience to address behavior and mood disorders; and research into mechanisms of cell death as part of efforts to identify therapies for neurodegenerative diseases that include amyotrophic lateral sclerosis (ALS) and Alzheimer's.
These methodological advances coupled with large, longitudinal studies of subjects progressing from healthy aging into dementia will enable a detailed understanding of the seeding and spread of these disorders.Neuroimaging has provided ample evidence that neurodegenerative disorders progress along brain networks, and is now beginning to elucidate how they do so.
Parkinson's disease (PD) is a neurodegenerative disorder of unknown cause that particularly affects areas of the brain which are involved in movement control.
«We are now working to understand how this newly recognized source of DNA damage might contribute to tumor development or the age - related DNA damage in the brain that is associated with neurodegenerative disorders like Alzheimer's disease,» said co-corresponding author Peter McKinnon, Ph.D., a member of the St. Jude Department of Genetics.
Specific Clinical / Research Interest: Experimental neuropathology, neurodegenerative disorders, brain aging; Functional anatomy of the cerebral cortex, comparative neuroanatomy; Computer - assisted morphometry, stereology, microscopy; Magnetic resonance microscopy, functional brain imaging Current Students: Tuyen Nguyen (PhD) Postdoctoral Fellows: Camilla Butti, PhD, Timothy Rumbell PhD, Merina Varghese PhD Research Personnel: Bridget Wicinski, Daniel Dickstein Summary of Research Studies: Our research is directed towards the study of selective neuronal vulnerability in dementing illnesses using classical neuropathological as well as modern quantitative immunohistochemical methods.
Neurodegenerative disorders like Huntington's disease affect very large brain areas.
The regional and laminar distribution in the cerebral cortex of specific neuronal populations is investigated in a variety of neurodegenerative disorders, and quantitatively compared to Alzheimer disease and control brains.
He also studies how dysregulated translational control contributes to altered synaptic function and aberrant behaviors in developmental brain disorders and neurodegenerative disease.
How does apoE4 contribute to the pathogenesis of Alzheimer's disease, traumatic brain injury, and other neurodegenerative disorders?
The company is also exploring the use of TAIs in several other neurodegenerative diseases associated with tau pathology, as well as other disorders deriving from the aggregation of other proteins in the brain, including Parkinson's and Huntington's.
However, neurodegenerative disorders, such as Alzheimer's disease, have been considered out of reach, because the underlying biology of the brain is so complicated.