Sentences with phrase «neurodegenerative disease and death»

A slow chain reaction occurs in the brain over the course of many years, leading to neurodegenerative disease and death.

Not exact matches

Neurodegenerative diseases are caused by the death of neurons and other cells in the brain, with different diseases affecting different regions of the brain.

The progressive degeneration and death of the brain, occurring in many neurodegenerative diseases, is often seen as an unstoppable and irrevocable process.

Researchers from Harvard Chan School and Brigham and Women's Hospital examined the relationship between types of fats in the participants» diets and overall deaths among the group during the study period, as well as deaths due to cardiovascular disease (CVD), cancer, neurodegenerative disease, and respiratory disease.

Alzheimer's disease is a neurodegenerative disease that results in cognitive decline, and eventually death.

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

«Our findings define a potential mechanism for neuronal cell death in Alexander disease and possibly other neurodegenerative diseases with astrocyte dysfunction.»

«Oxidative stress can cause damage to the building blocks of a cell, resulting in excessive cell proliferation, in the case of cancer or cell death, in the case of neurodegenerative diseases like Parkinson's,» said Mark Hannink, a professor in the Department of Biochemistry and an investigator at the Bond Life Sciences Center at MU.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a debilitating neurodegenerative disorder that leads to paralysis and death due to the loss of motor neurons in the brain and spinal cord.

It also may be an early warning sign of neurodegenerative diseases, such as Alzheimer's or Parkinson's, and can predict death.

Huntington's disease is a genetically determined neurodegenerative disorder that results in uncontrolled movements and, eventually, in cognitive decline and death.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by motor neuron death and muscle atrophy, and the RNA binding protein TDP - 43 has emerged as a major molecular factor in this disease.

It is the hope and desire of each of the contributing organizations that this effort will accelerate the development of a treatment for SMA, a devastating neurodegenerative disease that leads to death by age two in up to 50 % of patients.

These and other so - called neurodegenerative diseases are often associated with the buildup of toxic proteins that lead to neuronal death.

GM1 gangliosidosis, or Landing disease, is a rare inherited neurodegenerative lysosomal storage disorder characterized by severe cognitive and motor developmental delays resulting in the death of most patients at a very young age.

Core areas of research at the institute include work on brain - computer interfaces to aid patients with spinal injury and paralysis; innovative advances in computational neuroscience to address behavior and mood disorders; and research into mechanisms of cell death as part of efforts to identify therapies for neurodegenerative diseases that include amyotrophic lateral sclerosis (ALS) and Alzheimer's.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that leads to paralysis — and eventually death — due to the loss of motor neurons in the spinal cord and brain.

The good news is that replenishing NAD + to cells can restore DNA repair and prevent cell death under stress.26, 29 In two different animal models of neurodegenerative disease, increasing cellular NAD + reduced the severity of the disorder, normalized neuromuscular function, delayed memory loss, and extended lifespan.30